Pankajakshy A and Madambath I |
Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol. |
2009 |
Fertil. Steril. |
pmid:18692834
|
Wei J et al. |
Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists. |
2009 |
Cancer Lett. |
pmid:18782651
|
Azmi AS and Mohammad RM |
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy. |
2009 |
J. Cell. Physiol. |
pmid:18767026
|
Kang MH and Reynolds CP |
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. |
2009 |
Clin. Cancer Res. |
pmid:19228717
|
Lin J et al. |
[Effect of apogossypolone on induction apoptosis in multiple myeloma cells and its mechanisms]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:19236755
|
Przybylski P et al. |
Complexes of heterocyclic aza-derivatives of phytoalexin from cotton plant-gossypol with alkali metal cations and perchlorate anion studied by ESI mass spectrometric method in the positive and negative modes. |
2009 |
J Mass Spectrom |
pmid:19189269
|
Przybylski P et al. |
Antifungal activity of alkyl and heterocyclic aza-derivatives of gossypol as well as their complexes with NaClO4 against Fusarium oxysporum f. sp. lupini. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19264482
|
Verma PC et al. |
Efficient production of gossypol from hairy root cultures of cotton (Gossypium hirsutum L.). |
2009 |
Curr Pharm Biotechnol |
pmid:19751178
|
Sanli UA et al. |
Targeting apoptosis in the hormone- and drug-resistant prostate cancer cell line, DU-145, by gossypol/zoledronic acid combination. |
2009 |
Cell Biol. Int. |
pmid:19716895
|
Das SG et al. |
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. |
2009 |
J. Med. Chem. |
pmid:19743858
|
Hu ZY et al. |
ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
pmid:19698176
|
Kilic A et al. |
Efficacy of signal pathway inhibitors alone and in combination with Cisplatin varies between human non-small cell lung cancer lines. |
2009 |
J. Surg. Res. |
pmid:19084241
|
Chen BB et al. |
The (+)- and (-)-gossypols potently inhibit human and rat 11beta-hydroxysteroid dehydrogenase type 2. |
2009 |
J. Steroid Biochem. Mol. Biol. |
pmid:19150652
|
Stipanovic RD et al. |
Total and percent atropisomers of gossypol and gossypol-6-methyl ether in seeds from pima cottons and accessions of Gossypium barbadense L. |
2009 |
J. Agric. Food Chem. |
pmid:19113939
|
Zhang L et al. |
Chiral gossypol derivatives: evaluation of their anticancer activity and molecular modeling. |
2009 |
Eur J Med Chem |
pmid:19447525
|
Sun J et al. |
Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. |
2009 |
Oncol. Rep. |
pmid:19513523
|
Jiang J et al. |
Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling. |
2009 |
Int. J. Mol. Med. |
pmid:19513537
|
Przybylski P et al. |
Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant--gossypol. |
2009 |
Eur J Med Chem |
pmid:19577825
|
Wei J et al. |
Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2009 |
J. Med. Chem. |
pmid:19555126
|
Lestini BJ et al. |
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists. |
2009 |
Cancer Biol. Ther. |
pmid:19556859
|
Ionov M et al. |
The immobilization of gossypol derivative on N-polyvinylpyrrolidone increases its water solubility and modifies membrane-active properties. |
2009 |
J. Med. Chem. |
pmid:19603832
|
Anilkumar KJ et al. |
Synergistic interactions between Cry1Ac and natural cotton defenses limit survival of Cry1Ac-resistant Helicoverpa zea (Lepidoptera: Noctuidae) on Bt cotton. |
2009 |
J. Chem. Ecol. |
pmid:19588197
|
Huang YW et al. |
(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells. |
2009 |
Anticancer Res. |
pmid:19528479
|
Wang X et al. |
Gossypol--a polyphenolic compound from cotton plant. |
2009 |
Adv. Food Nutr. Res. |
pmid:19878861
|
Atmaca H et al. |
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
|
Zerp SF et al. |
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. |
2009 |
Radiat Oncol |
pmid:19852810
|
Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
|
Wu G et al. |
Temporal allocation of metabolic tolerance in the body of beet armyworm in response to three gossypol-cotton cultivars. |
2009 |
Sci. China, C, Life Sci. |
pmid:20016971
|
Roychoudhury S et al. |
In vitro gossypol induced spermatozoa motility alterations in rabbits. |
2009 |
J Environ Sci Health B |
pmid:20183084
|
Wang WQ et al. |
[Apoptosis of multiple myeloma cells induced by gossypol acetic acid in vitro and its mechanism]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:20030926
|
Karaca B et al. |
Enhancement of taxane-induced cytotoxicity and apoptosis by gossypol in human breast cancer cell line MCF-7. |
2009 Jul-Sep |
J BUON |
pmid:19810142
|
Schteingart DE et al. |
Expression of anti-apoptosis genes determines the response of adrenal cancer to apoptosis-inducing chemotherapy. |
2010 |
Anticancer Res. |
pmid:21187456
|
Cengiz E et al. |
Overcoming drug resistance in hormone- and drug-refractory prostate cancer cell line, PC-3 by docetaxel and gossypol combination. |
2010 |
Mol. Biol. Rep. |
pmid:19288219
|
Yan F et al. |
A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. |
2010 |
J. Med. Chem. |
pmid:20684596
|
Wu G et al. |
Responses of three successive generations of beet armyworm, Spodoptera exigua, fed exclusively on different levels of gossypol in cotton leaves. |
2010 |
J. Insect Sci. |
pmid:21067414
|
Wei J et al. |
Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2010 |
J. Med. Chem. |
pmid:21033669
|
ZHU Y et al. |
Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells. |
2010 |
Acta Pharmacol. Sin. |
pmid:21102482
|
Zhan WH et al. |
[Studies on the killing effect of gamma ray irradiated peripheral blood mononuclear cells combined with (-)-gossypol on human prostate cancer LNCaP cells]. |
2010 |
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi |
pmid:21319440
|
Sung B et al. |
Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. |
2010 |
J. Biol. Chem. |
pmid:20837473
|
Chang Q et al. |
Effects of combined administration of low-dose gossypol with steroid hormones on the mitotic phase of spermatogenesis of rat. |
2010 |
J Exp Zool A Ecol Genet Physiol |
pmid:20839281
|
Moretti L et al. |
AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20354451
|
Priyadarshi A et al. |
Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20206602
|
Reddish JM et al. |
(-)-Gossypol containing hen sera and a myosin (-)-gossypol conjugate reduces the proliferation of MCF-7 cells. |
2010 |
Anticancer Res. |
pmid:20332451
|
Banerjee S et al. |
Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells. |
2010 |
Pancreas |
pmid:19823097
|
Goldsmith KC et al. |
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists. |
2010 |
Cell Death Differ. |
pmid:19893570
|
Zhang XQ et al. |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol. |
2010 |
Asian J. Androl. |
pmid:20081872
|
Liu YX |
Temperature control of spermatogenesis and prospect of male contraception. |
2010 |
Front Biosci (Schol Ed) |
pmid:20036980
|
El-Sharaky AS et al. |
Spermatotoxicity, biochemical changes and histological alteration induced by gossypol in testicular and hepatic tissues of male rats. |
2010 |
Food Chem. Toxicol. |
pmid:20832445
|
Anuja MN et al. |
Spermatotoxicity of a protein isolated from the root of Achyranthes aspera: a comparative study with gossypol. |
2010 |
Contraception |
pmid:20851234
|
Li G et al. |
[Effect of testosterone on the expression of CMTM family of the male spermatogenesis suppression rats]. |
2010 |
Yao Xue Xue Bao |
pmid:21351585
|