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Synergistic combination of small molecule inhibitor and RNA interference against antiapoptotic Bcl-2 protein in head and neck cancer cells. |
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Mol. Pharm. |
pmid:23734725
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Efficacy of docetaxel-based chemotherapy following ketoconazole in metastatic castration-resistant prostate cancer: implications for prior therapy in clinical trials. |
2013 |
Urol. Oncol. |
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Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. |
2013 |
Cell Death Dis |
pmid:23807219
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Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway. |
2013 |
J. Vet. Sci. |
pmid:23820203
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Growth inhibition and apoptosis induction of human umbilical vein endothelial cells by apogossypolone. |
2013 |
Asian Pac. J. Cancer Prev. |
pmid:23679275
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Effects of temperature and medium composition on inhibitory activities of gossypol-related compounds against aflatoxigenic fungi. |
2013 |
J. Appl. Microbiol. |
pmid:23594138
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Poly(ethylene glycol)-block-poly(ε-caprolactone) micelles for combination drug delivery: evaluation of paclitaxel, cyclopamine and gossypol in intraperitoneal xenograft models of ovarian cancer. |
2013 |
J Control Release |
pmid:23246471
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Defective autophagy in multidrug resistant cells may lead to growth inhibition by BH3-mimetic gossypol. |
2013 |
J. Cell. Physiol. |
pmid:23254564
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Novel soluble myeloid cell leukemia sequence 1 (Mcl-1) inhibitor (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile (4g) developed using a fragment-based approach. |
2013 |
Eur J Med Chem |
pmid:23220642
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ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells. |
2013 |
Biomed. Pharmacother. |
pmid:23201009
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3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1. |
2013 |
Bioorg. Med. Chem. |
pmid:23206987
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The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells. |
2013 |
Cell Death Dis |
pmid:23392177
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Natural Bcl-2 inhibitor (-)- gossypol induces protective autophagy via reactive oxygen species-high mobility group box 1 pathway in Burkitt lymphoma. |
2013 |
Leuk. Lymphoma |
pmid:23398207
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Suppression of LPS-induced inflammatory responses by gossypol in RAW 264.7 cells and mouse models. |
2013 |
Int. Immunopharmacol. |
pmid:23352443
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A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. |
2013 |
Cell Stem Cell |
pmid:23333150
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Gossypol suppresses mouse T lymphocytes via inhibition of NFκB, NFAT and AP-1 pathways. |
2013 |
Immunopharmacol Immunotoxicol |
pmid:23981004
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BH3 mimetics: status of the field and new developments. |
2013 |
Mol. Cancer Ther. |
pmid:23974697
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Guo JY et al. |
Effects of high-gossypol cotton on the development and reproduction of Bemisia tabaci (Hemiptera: Aleyrodidae) MEAM1 cryptic species. |
2013 |
J. Econ. Entomol. |
pmid:23865205
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Zhang Z et al. |
Design and application of a rigid quinazolone scaffold based on two-face Bim α-helix mimicking. |
2013 |
Eur J Med Chem |
pmid:24095762
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Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells. |
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Mol. Biol. Rep. |
pmid:23269627
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