Cheng W et al. |
[Effect of gossypol acetate on proliferation and apoptosis in Raji lymphoblastoid cell line]. |
2009 |
Zhongguo Yi Xue Ke Xue Yuan Xue Bao |
pmid:19968063
|
Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
|
Wu G et al. |
Temporal allocation of metabolic tolerance in the body of beet armyworm in response to three gossypol-cotton cultivars. |
2009 |
Sci. China, C, Life Sci. |
pmid:20016971
|
Wang WQ et al. |
[Apoptosis of multiple myeloma cells induced by gossypol acetic acid in vitro and its mechanism]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:20030926
|
Xu P et al. |
Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol. |
2009 |
Anticancer Res. |
pmid:20032412
|
Liu YX |
Temperature control of spermatogenesis and prospect of male contraception. |
2010 |
Front Biosci (Schol Ed) |
pmid:20036980
|
Ford JM et al. |
Modulation of resistance to alkylating agents in cancer cell by gossypol enantiomers. |
1991 |
Cancer Lett. |
pmid:2004358
|
Zhang XQ et al. |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol. |
2010 |
Asian J. Androl. |
pmid:20081872
|
Volate SR et al. |
Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells. |
2010 |
Mol. Cancer Ther. |
pmid:20124455
|
Le A et al. |
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. |
2010 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:20133848
|
Kramer RY et al. |
The effect of cottonseed components on testicular development in pubescent rams. |
1991 |
Vet Hum Toxicol |
pmid:2017859
|
Roychoudhury S et al. |
In vitro gossypol induced spermatozoa motility alterations in rabbits. |
2009 |
J Environ Sci Health B |
pmid:20183084
|
Barelier S et al. |
Fragment-based deconstruction of Bcl-xL inhibitors. |
2010 |
J. Med. Chem. |
pmid:20192224
|
Priyadarshi A et al. |
Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20206602
|
Reddish JM et al. |
(-)-Gossypol containing hen sera and a myosin (-)-gossypol conjugate reduces the proliferation of MCF-7 cells. |
2010 |
Anticancer Res. |
pmid:20332451
|
Moretti L et al. |
AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20354451
|
Abe K et al. |
Phosphorylation of coagulation factor II by phospholipid/Ca(2+)-dependent protein kinase (protein kinase C). |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:2039497
|
Wei J et al. |
BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2010 |
J. Med. Chem. |
pmid:20443627
|
Kono H et al. |
Effects of progesterone and gossypol on monoamine oxidase activity in human term placental explant. |
1991 |
Tohoku J. Exp. Med. |
pmid:2048118
|
Fulda S |
Modulation of apoptosis by natural products for cancer therapy. |
2010 |
Planta Med. |
pmid:20486070
|
|
|
|
|
pmid:20496676
|
Ye W et al. |
Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells. |
2010 |
Int. J. Mol. Med. |
pmid:20514430
|
Gao P et al. |
The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. |
2010 |
J. Biol. Chem. |
pmid:20529838
|
Sahin F et al. |
Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity. |
2010 |
Hematology |
pmid:20557672
|
D'Cruz SC et al. |
Effects of plants and plant products on the testis. |
2010 |
Asian J. Androl. |
pmid:20562897
|
Lian J et al. |
A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. |
2011 |
Cell Death Differ. |
pmid:20577262
|
Voss V et al. |
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. |
2010 |
Mol. Cancer Res. |
pmid:20587533
|
McGregor N et al. |
AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model. |
2010 |
J. Cell. Biochem. |
pmid:20589722
|
Khadzhibaev GS et al. |
[Interferonogenic activity of gossypol, a low-molecular substance]. |
1978 |
Antibiotiki |
pmid:206198
|
Huang LH et al. |
Gossypol inhibits phosphorylation of Bcl-2 in human leukemia HL-60 cells. |
2010 |
Eur. J. Pharmacol. |
pmid:20633548
|
Kono H et al. |
Gossypol effects on monoamine oxidase (MAO) activity in several organs of term rats. |
1991 |
Tohoku J. Exp. Med. |
pmid:2063399
|
Tiliabaev KZ et al. |
[Synthesis, structures, and acute toxicity of gossypol nonsymmetrical aldehyde derivatives]. |
2010 May-Jun |
Bioorg. Khim. |
pmid:20644599
|
Gu Y et al. |
Gossypolone suppresses progesterone synthesis in bovine luteal cells. |
1991 |
J. Steroid Biochem. Mol. Biol. |
pmid:2064986
|
Zhang XQ et al. |
Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro. |
2010 |
Asian J. Androl. |
pmid:20657602
|
Yan F et al. |
A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. |
2010 |
J. Med. Chem. |
pmid:20684596
|
Blevins S et al. |
Effects of silymarin on gossypol toxicosis in divergent lines of chickens. |
2010 |
Poult. Sci. |
pmid:20709972
|
Taylor GT et al. |
Search for a male contraceptive: the effect of gossypol on sexual motivation and epididymal sperm. |
1991 |
J Med |
pmid:2072049
|
Ikeda M |
Inhibition kinetics of NAD-linked enzymes by gossypol acetic acid. |
1990 Sep-Oct |
Andrologia |
pmid:2073051
|
Kalla NR et al. |
Response of mice testis to gossypol acetic acid. |
1990 Jan-Feb |
Acta Eur. Fertil. |
pmid:2075791
|
Kalla NR et al. |
Effect of gossypol on domestic fowl, Gallus domesticus. |
1990 Jan-Feb |
Acta Eur. Fertil. |
pmid:2075792
|
Vyas RK et al. |
Recovery of normal testis function and sperm motility after cessation of gossypol treatment in hamster. |
1990 Jan-Feb |
Acta Eur. Fertil. |
pmid:2075793
|
Kalla NR |
Gossypol. |
1990 Jan-Feb |
Acta Eur. Fertil. |
pmid:2075794
|
Heist RS et al. |
Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20808253
|
Lei HQ and Xu YX |
[Effects of gossypol acetic acid on transport and development of fertilized eggs in rats]. |
1990 |
Yao Xue Xue Bao |
pmid:2082677
|
Kunesch N et al. |
[Preparation of derivatives of the aldehydic functions of gossypol]. |
1990 |
Ann Pharm Fr |
pmid:2082795
|
El-Sharaky AS et al. |
Spermatotoxicity, biochemical changes and histological alteration induced by gossypol in testicular and hepatic tissues of male rats. |
2010 |
Food Chem. Toxicol. |
pmid:20832445
|
Johansen RL and Misra HP |
Effects of gossypol on the hepatic drug metabolizing system in rats. |
1990 |
Contraception |
pmid:2083490
|
Sung B et al. |
Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. |
2010 |
J. Biol. Chem. |
pmid:20837473
|
Chang Q et al. |
Effects of combined administration of low-dose gossypol with steroid hormones on the mitotic phase of spermatogenesis of rat. |
2010 |
J Exp Zool A Ecol Genet Physiol |
pmid:20839281
|
Uzunoglu S et al. |
Comparison of XTT and Alamar blue assays in the assessment of the viability of various human cancer cell lines by AT-101 (-/- gossypol). |
2010 |
Toxicol. Mech. Methods |
pmid:20843265
|