Politzer WM |
Long-term clinical remission of a patient with chronic lymphocytic leukemia using alternative treatment option: cottonseed oil (gossypol). |
2008 |
Phytomedicine |
pmid:18573644
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Shaaban WF et al. |
Reproductive toxicologic effects of gossypol on male rabbits: biochemical, enzymatic, and electrolytic properties of seminal plasma. |
2008 |
Fertil. Steril. |
pmid:17953964
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Tang G et al. |
Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins. |
2008 |
J. Med. Chem. |
pmid:18237106
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Kline MP et al. |
R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. |
2008 |
Exp. Hematol. |
pmid:18346839
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Gao F et al. |
Interactive effects of elevated CO2 and cotton cultivar on tri-trophic interaction of Gossypium hirsutum, Aphis gossyppii, and Propylaea japonica. |
2008 |
Environ. Entomol. |
pmid:18348793
|
Moon DO et al. |
Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells. |
2008 |
Cancer Lett. |
pmid:18314260
|
Sprogøe K et al. |
Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: levorotatory gossypol in Thespesia danis. |
2008 |
J. Nat. Prod. |
pmid:18290629
|
Paoluzzi L et al. |
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma. |
2008 |
Blood |
pmid:18292288
|
Przybylski P et al. |
CP/MAS spectroscopy in the determination of the tautomeric forms of gossypol, its Schiff bases and hydrazones in the solid state. |
2008 |
Magn Reson Chem |
pmid:18338327
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Zha SW et al. |
[Male antifertility drugs and cell apoptosis]. |
2008 |
Zhonghua Nan Ke Xue |
pmid:18297819
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RodrÃguez-EnrÃquez S et al. |
Energy metabolism transition in multi-cellular human tumor spheroids. |
2008 |
J. Cell. Physiol. |
pmid:18264981
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Villaseñor M et al. |
Gossypol disrupts embryo development in heifers. |
2008 |
J. Dairy Sci. |
pmid:18650278
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Aoyama K |
[Determination of gossypol in feeds by HPLC]. |
2008 |
Shokuhin Eiseigaku Zasshi |
pmid:18787315
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Sun Y et al. |
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo. |
2008 |
Cancer Biol. Ther. |
pmid:18769131
|
Moon DO et al. |
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT. |
2008 |
FEBS Lett. |
pmid:18775705
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Przybylski P et al. |
Molecular structures and stability constants of gossypol and its aza-derivative complexes with silver(I) cations studied by potentiometric, ESI MS, NMR, and AM1d semiempirical methods. |
2008 |
J Phys Chem A |
pmid:18698745
|
Boonsri S et al. |
Cytotoxic and antibacterial sesquiterpenes from Thespesia populnea. |
2008 |
J. Nat. Prod. |
pmid:18553924
|
Zhou DR et al. |
Gossypol repressed the gap junctional intercellular communication between Sertoli cells by decreasing the expression of Connexin43. |
2008 |
Toxicol In Vitro |
pmid:18706992
|
Etxebarria A et al. |
Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems. |
2008 |
Biochem. Pharmacol. |
pmid:18762177
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Cui G et al. |
Gossypol with methyltestosterone and ethinylestradiol male does not affect rat spermatogonial stem cell differentiation. |
2007 Mar-Apr |
Arch. Androl. |
pmid:17453689
|
Ye W et al. |
Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil. |
2007 Jan-Feb |
Anticancer Res. |
pmid:17352222
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Meng Y et al. |
(-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells. |
2007 |
Leuk. Lymphoma |
pmid:17926190
|
Mao YB et al. |
Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol. |
2007 |
Nat. Biotechnol. |
pmid:17982444
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Lordelo MM et al. |
Relative toxicity of gossypol enantiomers in laying and broiler breeder hens. |
2007 |
Poult. Sci. |
pmid:17297172
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Zhang M et al. |
Differential growth inhibition and induction of apoptosis by gossypol between HCT116 and HCT116/Bax(-/-) colorectal cancer cells. |
2007 |
Clin. Exp. Pharmacol. Physiol. |
pmid:17250644
|
Leyman A et al. |
The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts. |
2007 |
Cell. Signal. |
pmid:17355905
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Costantino A et al. |
Current status and future perspectives in male contraception. |
2007 |
Minerva Ginecol |
pmid:17576406
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Tang G et al. |
Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic Bcl-2 proteins. |
2007 |
J. Med. Chem. |
pmid:17552510
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Ko CH et al. |
Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells. |
2007 |
Int. J. Cancer |
pmid:17597109
|
Wolter KG et al. |
Therapeutic window for melanoma treatment provided by selective effects of the proteasome on Bcl-2 proteins. |
2007 |
Cell Death Differ. |
pmid:17541428
|
Kasten-Pisula U et al. |
Radiosensitization of tumour cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis. |
2007 |
Radiother Oncol |
pmid:17521756
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Feng BY et al. |
A high-throughput screen for aggregation-based inhibition in a large compound library. |
2007 |
J. Med. Chem. |
pmid:17447748
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Badawy SZ et al. |
Gossypol inhibits proliferation of endometrioma cells in culture. |
2007 |
Asian J. Androl. |
pmid:17486280
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Orth RG et al. |
Determining larval host plant use by a polyphagous lepidopteran through analysis of adult moths for plant secondary metabolites. |
2007 |
J. Chem. Ecol. |
pmid:17492366
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Choi SR et al. |
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors. |
2007 |
J. Med. Chem. |
pmid:17636950
|
Loberg RD et al. |
In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen-independent growth of VCaP prostate cancer cells in combination with surgical castration. |
2007 |
Neoplasia |
pmid:18084610
|
Turco E et al. |
The in vitro effect of gossypol and its interaction with salts on conidial germination and viability of Fusarium oxysporum sp. vasinfectum isolates. |
2007 |
J. Appl. Microbiol. |
pmid:18045422
|
Akinola OB et al. |
Spermatoprotective activity of the leaf extract of Psidium guajava Linn. |
2007 |
Niger Postgrad Med J |
pmid:18163132
|
Gerasimidis K et al. |
Preparation of an edible cottonseed protein concentrate and evaluation of its functional properties. |
2007 |
Int J Food Sci Nutr |
pmid:17710592
|
Carruthers NJ et al. |
Gossypol inhibits calcineurin phosphatase activity at multiple sites. |
2007 |
Eur. J. Pharmacol. |
pmid:17141216
|
Liu F et al. |
Pharmacophore identification of KSP inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17095225
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Zhang M et al. |
Gossypol induces apoptosis in human PC-3 prostate cancer cells by modulating caspase-dependent and caspase-independent cell death pathways. |
2007 |
Life Sci. |
pmid:17156797
|
Song JJ et al. |
Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL. |
2007 |
J. Biol. Chem. |
pmid:17110373
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Xing C et al. |
Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1. |
2007 |
Bioorg. Med. Chem. |
pmid:17227711
|
Lv G et al. |
[The effect of gossypol, praziquantel and artemether on recombinant lactate dehydrogenase from Schistosoma japonicum]. |
2007 |
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi |
pmid:18441994
|
Denisov AY et al. |
Heat-induced dimerization of BCL-xL through alpha-helix swapping. |
2007 |
Biochemistry |
pmid:17223694
|
Makkar HP et al. |
Plant secondary metabolites. |
2007 |
Methods Mol. Biol. |
pmid:19238775
|
Huang YW et al. |
Effects of serum on (-)-gossypol-suppressed growth in human prostate cancer cells. |
2006 Sep-Oct |
Anticancer Res. |
pmid:17094491
|
Huang YW et al. |
Molecular mechanisms of (-)-gossypol-induced apoptosis in human prostate cancer cells. |
2006 May-Jun |
Anticancer Res. |
pmid:16827126
|
Akinola OB et al. |
Proteinaceous diet inhibits gossypol-induced spermatotoxicity. |
2006 Jul-Sep |
Eur J Histochem |
pmid:16920644
|