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Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. |
2013 |
Cell Death Dis |
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Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway. |
2013 |
J. Vet. Sci. |
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Growth inhibition and apoptosis induction of human umbilical vein endothelial cells by apogossypolone. |
2013 |
Asian Pac. J. Cancer Prev. |
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Effects of temperature and medium composition on inhibitory activities of gossypol-related compounds against aflatoxigenic fungi. |
2013 |
J. Appl. Microbiol. |
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Gossypol suppresses mouse T lymphocytes via inhibition of NFκB, NFAT and AP-1 pathways. |
2013 |
Immunopharmacol Immunotoxicol |
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Mol. Cancer Ther. |
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Zh. Mikrobiol. Epidemiol. Immunobiol. |
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Molecular screening of insecticides with sigma glutathione S-transferases (GST) in cotton aphid Aphis gossypii using docking. |
2014 |
Bioinformation |
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Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway. |
2014 |
Drug Des Devel Ther |
pmid:25548514
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Gossypol promotes degeneration of ovarian follicles in rats. |
2014 |
ScientificWorldJournal |
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Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models. |
2014 |
Br. J. Cancer |
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Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway. |
2014 |
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AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenström macroglobulinaemia. |
2014 |
Br. J. Haematol. |
pmid:24236538
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Therapeutic potential of gossypol: an overview. |
2014 |
Pharm Biol |
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Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. |
2014 |
J. Biol. Chem. |
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2014 |
Poult. Sci. |
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Targeting BCL2 for the treatment of lymphoid malignancies. |
2014 |
Semin. Hematol. |
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Invest New Drugs |
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