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2011 |
J Thorac Oncol |
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Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
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(-)-Gossypol suppresses the growth of human prostate cancer xenografts via modulating VEGF signaling-mediated angiogenesis. |
2011 |
Mol. Cancer Ther. |
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2011 |
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2011 |
Toxicology |
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Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells. |
2011 |
Mol. Cancer Res. |
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Radiosensitization of hormone-refractory prostate cancer cells by gossypol treatment. |
2010 Oct-Dec |
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2010 May-Jun |
Bioorg. Khim. |
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The influence of protonation on molecular structure and physico-chemical properties of gossypol Schiff bases. |
2010 |
Org. Biomol. Chem. |
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2010 |
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2010 |
J Thorac Oncol |
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The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells. |
2010 |
Autophagy |
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Aromatase expression in leptin-pretreated human breast pre-adipocytes is enhanced by zeranol and suppressed by (-)-gossypol. |
2010 |
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BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2010 |
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The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. |
2010 |
Mol. Cancer Res. |
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AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model. |
2010 |
J. Cell. Biochem. |
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Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro. |
2010 |
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Gossypol inhibits phosphorylation of Bcl-2 in human leukemia HL-60 cells. |
2010 |
Eur. J. Pharmacol. |
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2010 |
Int. J. Mol. Med. |
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Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity. |
2010 |
Hematology |
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