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A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. |
2010 |
J. Med. Chem. |
pmid:20684596
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Responses of three successive generations of beet armyworm, Spodoptera exigua, fed exclusively on different levels of gossypol in cotton leaves. |
2010 |
J. Insect Sci. |
pmid:21067414
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Wei J et al. |
Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2010 |
J. Med. Chem. |
pmid:21033669
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ZHU Y et al. |
Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells. |
2010 |
Acta Pharmacol. Sin. |
pmid:21102482
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Moretti L et al. |
AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20354451
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Priyadarshi A et al. |
Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20206602
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Reddish JM et al. |
(-)-Gossypol containing hen sera and a myosin (-)-gossypol conjugate reduces the proliferation of MCF-7 cells. |
2010 |
Anticancer Res. |
pmid:20332451
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Zhang XQ et al. |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol. |
2010 |
Asian J. Androl. |
pmid:20081872
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Liu YX |
Temperature control of spermatogenesis and prospect of male contraception. |
2010 |
Front Biosci (Schol Ed) |
pmid:20036980
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El-Sharaky AS et al. |
Spermatotoxicity, biochemical changes and histological alteration induced by gossypol in testicular and hepatic tissues of male rats. |
2010 |
Food Chem. Toxicol. |
pmid:20832445
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Karaca B et al. |
Enhancement of taxane-induced cytotoxicity and apoptosis by gossypol in human breast cancer cell line MCF-7. |
2009 Jul-Sep |
J BUON |
pmid:19810142
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Zhan Y et al. |
Design and synthesis of a gossypol derivative with improved antitumor activities. |
2009 |
Arch. Pharm. (Weinheim) |
pmid:19340835
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Efficient production of gossypol from hairy root cultures of cotton (Gossypium hirsutum L.). |
2009 |
Curr Pharm Biotechnol |
pmid:19751178
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Sanli UA et al. |
Targeting apoptosis in the hormone- and drug-resistant prostate cancer cell line, DU-145, by gossypol/zoledronic acid combination. |
2009 |
Cell Biol. Int. |
pmid:19716895
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Das SG et al. |
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. |
2009 |
J. Med. Chem. |
pmid:19743858
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Hu ZY et al. |
ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
pmid:19698176
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Wang X et al. |
Gossypol--a polyphenolic compound from cotton plant. |
2009 |
Adv. Food Nutr. Res. |
pmid:19878861
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Atmaca H et al. |
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
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Zerp SF et al. |
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. |
2009 |
Radiat Oncol |
pmid:19852810
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Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
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