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Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol. |
2009 |
Fertil. Steril. |
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Complexes of heterocyclic aza-derivatives of phytoalexin from cotton plant-gossypol with alkali metal cations and perchlorate anion studied by ESI mass spectrometric method in the positive and negative modes. |
2009 |
J Mass Spectrom |
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Przybylski P et al. |
Antifungal activity of alkyl and heterocyclic aza-derivatives of gossypol as well as their complexes with NaClO4 against Fusarium oxysporum f. sp. lupini. |
2009 |
Bioorg. Med. Chem. Lett. |
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Balakrishnan K et al. |
AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. |
2009 |
Blood |
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2009 |
Clin. Cancer Res. |
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2009 |
Mol. Cancer Ther. |
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The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis. |
2009 |
Acta Pharmacol. Sin. |
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Design and synthesis of a gossypol derivative with improved antitumor activities. |
2009 |
Arch. Pharm. (Weinheim) |
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2009 |
Curr Pharm Biotechnol |
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Targeting apoptosis in the hormone- and drug-resistant prostate cancer cell line, DU-145, by gossypol/zoledronic acid combination. |
2009 |
Cell Biol. Int. |
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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. |
2009 |
J. Med. Chem. |
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ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
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The immobilization of gossypol derivative on N-polyvinylpyrrolidone increases its water solubility and modifies membrane-active properties. |
2009 |
J. Med. Chem. |
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Synergistic interactions between Cry1Ac and natural cotton defenses limit survival of Cry1Ac-resistant Helicoverpa zea (Lepidoptera: Noctuidae) on Bt cotton. |
2009 |
J. Chem. Ecol. |
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(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells. |
2009 |
Anticancer Res. |
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Can gossypol be a hope for transsexual patients (male to female) before sex reassignment surgery? Just for adjusting the body to mind. |
2009 |
Med. Hypotheses |
pmid:19647947
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Mutual anti-oxidative effect of gossypol acetic acid and gossypol-iron complex on hepatic lipid peroxidation in male rats. |
2009 |
Food Chem. Toxicol. |
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The (+)- and (-)-gossypols potently inhibit both 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 in human and rat testes. |
2009 |
J. Steroid Biochem. Mol. Biol. |
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Gossypol induced apoptosis of polymorphonuclear leukocytes and monocytes: involvement of mitochondrial pathway and reactive oxygen species. |
2009 |
Immunopharmacol Immunotoxicol |
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Gossypol, a polyphenolic aldehyde from cotton plant, interferes with swine granulosa cell function. |
2009 |
Domest. Anim. Endocrinol. |
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2009 |
Adv. Food Nutr. Res. |
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Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
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AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. |
2009 |
Radiat Oncol |
pmid:19852810
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The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
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Temporal allocation of metabolic tolerance in the body of beet armyworm in response to three gossypol-cotton cultivars. |
2009 |
Sci. China, C, Life Sci. |
pmid:20016971
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In vitro gossypol induced spermatozoa motility alterations in rabbits. |
2009 |
J Environ Sci Health B |
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[Apoptosis of multiple myeloma cells induced by gossypol acetic acid in vitro and its mechanism]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
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Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol. |
2009 |
Anticancer Res. |
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[Effect of gossypol acetate on proliferation and apoptosis in Raji lymphoblastoid cell line]. |
2009 |
Zhongguo Yi Xue Ke Xue Yuan Xue Bao |
pmid:19968063
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Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19386788
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Enhancement of taxane-induced cytotoxicity and apoptosis by gossypol in human breast cancer cell line MCF-7. |
2009 Jul-Sep |
J BUON |
pmid:19810142
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Fulda S |
Modulation of apoptosis by natural products for cancer therapy. |
2010 |
Planta Med. |
pmid:20486070
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The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix. |
2010 |
Cell. Mol. Biol. Lett. |
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Effects of silymarin on gossypol toxicosis in divergent lines of chickens. |
2010 |
Poult. Sci. |
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A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. |
2010 |
J. Med. Chem. |
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The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells. |
2010 |
Autophagy |
pmid:20930561
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Aromatase expression in leptin-pretreated human breast pre-adipocytes is enhanced by zeranol and suppressed by (-)-gossypol. |
2010 |
Anticancer Res. |
pmid:21187493
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Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20808253
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AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model. |
2010 |
J. Cell. Biochem. |
pmid:20589722
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Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro. |
2010 |
Asian J. Androl. |
pmid:20657602
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Gossypol inhibits phosphorylation of Bcl-2 in human leukemia HL-60 cells. |
2010 |
Eur. J. Pharmacol. |
pmid:20633548
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Ye W et al. |
Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells. |
2010 |
Int. J. Mol. Med. |
pmid:20514430
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Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity. |
2010 |
Hematology |
pmid:20557672
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Effects of plants and plant products on the testis. |
2010 |
Asian J. Androl. |
pmid:20562897
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The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. |
2010 |
J. Biol. Chem. |
pmid:20529838
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Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells. |
2010 |
Mol. Cancer Ther. |
pmid:20124455
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2010 |
J. Med. Chem. |
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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. |
2010 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:20133848
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Zhang XQ et al. |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol. |
2010 |
Asian J. Androl. |
pmid:20081872
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Inhibition of calcineurin by quercetin in vitro and in Jurkat cells. |
2010 |
J. Biochem. |
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