Gawande ND et al. |
Molecular screening of insecticides with sigma glutathione S-transferases (GST) in cotton aphid Aphis gossypii using docking. |
2014 |
Bioinformation |
pmid:25512683
|
Ren T et al. |
Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway. |
2014 |
Drug Des Devel Ther |
pmid:25548514
|
Gadelha IC et al. |
Gossypol promotes degeneration of ovarian follicles in rats. |
2014 |
ScientificWorldJournal |
pmid:25540815
|
Jarzabek MA et al. |
Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models. |
2014 |
Br. J. Cancer |
pmid:25375271
|
Sadahira K et al. |
Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway. |
2014 |
Int. J. Oncol. |
pmid:25231749
|
Kogan P and Wald M |
Male contraception: history and development. |
2014 |
Urol. Clin. North Am. |
pmid:24286773
|
Paulus A et al. |
AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenström macroglobulinaemia. |
2014 |
Br. J. Haematol. |
pmid:24236538
|
Keshmiri-Neghab H and Goliaei B |
Therapeutic potential of gossypol: an overview. |
2014 |
Pharm Biol |
pmid:24073600
|
Mellon JE et al. |
Growth inhibitory effects of gossypol and related compounds on fungal cotton root pathogens. |
2014 |
Lett. Appl. Microbiol. |
pmid:24713043
|
Cho H et al. |
Polymeric micelles for apoptosis-targeted optical imaging of cancer and intraoperative surgical guidance. |
2014 |
PLoS ONE |
pmid:24587157
|
Sonpavde G et al. |
Radiographic progression by Prostate Cancer Working Group (PCWG)-2 criteria as an intermediate endpoint for drug development in metastatic castration-resistant prostate cancer. |
2014 |
BJU Int. |
pmid:24298897
|
Soderquist RS et al. |
Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. |
2014 |
J. Biol. Chem. |
pmid:24778183
|
Zeng QF et al. |
Effects of dietary gossypol concentration on growth performance, blood profiles, and hepatic histopathology in meat ducks. |
2014 |
Poult. Sci. |
pmid:24902707
|
Anderson MA et al. |
Targeting BCL2 for the treatment of lymphoid malignancies. |
2014 |
Semin. Hematol. |
pmid:25048785
|
Schelman WR et al. |
A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer. |
2014 |
Invest New Drugs |
pmid:23860642
|
Paulus A et al. |
The investigational agent MLN2238 induces apoptosis and is cytotoxic to CLL cells in vitro, as a single agent and in combination with other drugs. |
2014 |
Br. J. Haematol. |
pmid:24467634
|
Jang GH and Lee M |
BH3-mimetic gossypol-induced autophagic cell death in mutant BRAF melanoma cells with high expression of p21Cip¹.). |
2014 |
Life Sci. |
pmid:24625733
|
Li G et al. |
RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo. |
2014 |
Cell Death Dis |
pmid:24434521
|
Mei H et al. |
Autophagy inhibition enhances pan-Bcl-2 inhibitor AT-101-induced apoptosis in non-small cell lung cancer. |
2014 |
Neoplasma |
pmid:24299314
|
Spijkers-Hagelstein JA et al. |
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101. |
2014 |
Eur. J. Cancer |
pmid:24703900
|