Teng CS |
Biological activity in the repopulating rat spermatocyte after the withdrawal of gossypol treatment: III. The activity for the transcription of messenger RNA. |
1992 |
Contraception |
pmid:1559338
|
Srivastava A et al. |
Studies on mechanism(s) of antifertility action of gossypol in rat and hamster. |
1989 |
Contraception |
pmid:2469550
|
Moore GD et al. |
Inhibition of sperm migration, fertilization and implantation in rats by precoital intrauterine administration of gossypol or nonoxynol-9. |
1988 |
Contraception |
pmid:2835205
|
Fu YF et al. |
Effects of gossypol on the activity of kidney (Na+ + K+)-ATPase and the functions of erythrocyte membrane. |
1988 |
Contraception |
pmid:2836126
|
White IG et al. |
Studies of the mechanism of action of gossypol as a male antifertility agent. |
1988 |
Contraception |
pmid:2836127
|
van Ypersele de Strihou C et al. |
Effects of gossypol on the kidney with special emphasis on potassium (K) excretion. |
1988 |
Contraception |
pmid:3370990
|
Heywood R |
The toxicology of gossypol acetic acid and (-)-gossypol. |
1988 |
Contraception |
pmid:3370991
|
Wang RL et al. |
Gossypol acetate-induced SCEs in spermatogonia and bone marrow cells of mice: dose-response relationships. |
1988 |
Contraception |
pmid:3370992
|
Hahn DW et al. |
Antifertility and endocrine activities of gossypol in rodents. |
1981 |
Contraception |
pmid:7273769
|
Waller DP et al. |
Antifertility effects of gossypol and its impurities on male hamsters. |
1981 |
Contraception |
pmid:7285581
|
Chang MC et al. |
Effects of Gossypol on the fertility of male rats, hamsters and rabbits. |
1980 |
Contraception |
pmid:7428357
|
Sakesena SK et al. |
Gossypol: its toxicological and endocrinological effects in male rabbits. |
1981 |
Contraception |
pmid:7297071
|
Tso WW and Lee CS |
Variations of gossypol sensitivity in boar spermatozoal electron transport chain segments. |
1981 |
Contraception |
pmid:7318437
|
Tanphaichitr N and Fitzgerald LM |
Adverse effects of gossypol analogs on TM4 cell mitochondrial function. |
1989 |
Contraception |
pmid:2752754
|
Tanphaichitr N et al. |
Inhibitory effects of gossypol analogs on human sperm motility. |
1989 |
Contraception |
pmid:2752755
|
Whaley KJ et al. |
Monkey lactate dehydrogenase-C4 as a model for the interaction of enzymes with gossypol. |
1986 |
Contraception |
pmid:3769483
|
Ojha P et al. |
Effect of antispermatogenic agents on cell marker enzymes of rat Sertoli cells in vitro. |
2006 |
Contraception |
pmid:16371305
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Ueno H et al. |
Interaction of gossypol with sperm macromolecules and enzymes. |
1988 |
Contraception |
pmid:2967157
|
Ma XN and Back DJ |
Inhibition of hepatic microsomal enzymes by gossypol in the rat. |
1984 |
Contraception |
pmid:6478834
|
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International Symposium on Gossypol Research for Fertility Regulation. Wuhan, China, 15-17 October 1986. Representative papers. |
1988 |
Contraception |
pmid:3370985
|
Liu GZ et al. |
Effects of K salt or a potassium blocker on gossypol-related hypokalemia. |
1988 |
Contraception |
pmid:3370986
|
Frick J et al. |
Clinical microdose study of gossypol: effect on sperm motility and renal function. |
1988 |
Contraception |
pmid:3370988
|
Kainz P et al. |
Effect of gossypol on macromolecular synthesis in rat testis. An in vitro study. |
1985 |
Contraception |
pmid:2580663
|
Drayer DE and Reidenberg MM |
Gossypol and Na+, K+ ATPase from human erythrocytes. |
1988 |
Contraception |
pmid:2848657
|
Xue SP et al. |
Evaluation of the renal tubulo-toxic effect of gossypol by urinary protein analysis with SDS-polyacrylamide gel electrophoresis. |
1988 |
Contraception |
pmid:3370989
|
Beaudoin AR |
A developmental toxicity evaluation of gossypol. |
1988 |
Contraception |
pmid:3370993
|
Benz C et al. |
Selective toxicity of gossypol against epithelial tumors and its detection by magnetic resonance spectroscopy. |
1988 |
Contraception |
pmid:3370994
|
Matlin SA et al. |
Large-scale resolution of gossypol enantiomers for biological evaluation. |
1988 |
Contraception |
pmid:3370995
|
Zhou RH and Lin XD |
Isolation of (-)-gossypol from natural plant. |
1988 |
Contraception |
pmid:3370996
|
Sonenberg M et al. |
Anti-fertility and other actions of gossypol analogues. |
1988 |
Contraception |
pmid:3370997
|
Stumpf WE et al. |
Sites of action of gossypol studied by autoradiography and enzyme histochemistry. |
1988 |
Contraception |
pmid:3370998
|
Ratsula K et al. |
Vaginal contraception with gossypol: a clinical study. |
1983 |
Contraception |
pmid:6684533
|
Fei RR and Teng CS |
The effects of gossypol on nuclear protein in rat testes. I. Reduction in the content of basic proteins in the spermiogenic cells. |
1988 |
Contraception |
pmid:3370999
|
Teng CS and Fei RR |
The effects of gossypol on nuclear protein in rat testes. II. The synthesis of histones and testis-specific proteins after gossypol treatment. |
1988 |
Contraception |
pmid:3371000
|
Hoffer AP et al. |
Antifertility, spermicidal and ultrastructural effects of gossypol and derivatives administered orally and by intratesticular injections. |
1988 |
Contraception |
pmid:3371001
|
Yang ZJ et al. |
Combined administration of low-dose gossypol acetic acid with desogestrel/mini-dose ethinylestradiol/testosterone undecanoate as an oral contraceptive for men. |
2004 |
Contraception |
pmid:15325889
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Kumar M et al. |
Gossypol-induced hypokalemia and role of exogenous potassium salt supplementation when used as an antispermatogenic agent in male langur monkey. |
1997 |
Contraception |
pmid:9408707
|
Wu DF and Reidenberg MM |
Stereoselective interaction between gossypol and rat plasma. |
1990 |
Contraception |
pmid:2335102
|
Lin YC et al. |
Effect of gossypol on thyroid hormones in young female rats. |
1990 |
Contraception |
pmid:2335106
|
Kanwar U et al. |
Gossypol-induced inhibition of glucose uptake in human ejaculated spermatozoa may be mediated by lipid peroxidation. |
1990 |
Contraception |
pmid:2272185
|
Kim I et al. |
Inhibition of lactate dehydrogenase-X by imino-derivatives of gossypol:structure activity relationship. |
1987 |
Contraception |
pmid:3608484
|
Sinha Hikim AP and Hoffer AP |
Quantitative analysis of germ cells and Leydig cells in rat made infertile with gossypol. |
1987 |
Contraception |
pmid:3621939
|
Achedume AC et al. |
Biochemical studies of the effect of gossypol consumption on cholesterol and residual glucose in fed and protein-energy deficient rats. |
1994 |
Contraception |
pmid:7813227
|
Kanwar U et al. |
Gossypol inhibition of Ca++ uptake and Ca++-ATPase in human ejaculated spermatozoal plasma membrane vesicles. |
1989 |
Contraception |
pmid:2541968
|
Teng CS |
Reversible changes in the content of cellular and microtubular tubulin in spermatogenic cells after gossypol treatment. |
1997 |
Contraception |
pmid:9013060
|
Bansode FW |
Genotoxic effects of gossypol acetate on the ovary of Rhinopoma kinneari wroughton (Microchiroptera: Mammalia). |
1994 |
Contraception |
pmid:8070265
|
Kainz P et al. |
The in vivo effect of gossypol on macromolecular synthesis in rat testis. |
1985 |
Contraception |
pmid:2419026
|
Polsky B et al. |
Inactivation of human immunodeficiency virus in vitro by gossypol. |
1989 |
Contraception |
pmid:2473865
|
Bender HS et al. |
A histopathologic study of the effects of gossypol on the female rat. |
1988 |
Contraception |
pmid:3197423
|
Nwoha PU |
The blood constituents of gossypol-treated, protein-malnourished Wistar rats. |
1995 |
Contraception |
pmid:8605784
|
Nwoha PU and Aire TA |
The effects of gossypol and chloroquine interaction on serum electrolytes of protein-malnourished rats. |
1995 |
Contraception |
pmid:8605785
|
Nwoha PU and Aire TA |
Reduced level of serum cholesterol in low protein-fed Wistar rats administered gossypol and chloroquine. |
1995 |
Contraception |
pmid:8605786
|
Orhan G et al. |
The effect of the male contraceptive agent gossypol acetic acid on mouse bone marrow cells in vivo: micronuclei and mitotic index. |
1993 |
Contraception |
pmid:8508667
|
González-Garza MT et al. |
Orally administered gossypol has no effect on eight hamster erythrocytic enzymes. |
1995 |
Contraception |
pmid:8749602
|
Teng CS |
Gossypol-induced apoptotic DNA fragmentation correlates with inhibited protein kinase C activity in spermatocytes. |
1995 |
Contraception |
pmid:8749604
|
Wang C and Yeung RT |
Gossypol and hypokalaemia. |
1985 |
Contraception |
pmid:3910352
|
Yuan YY and Shi QX |
Inhibition of hamster sperm acrosomal enzyme by gossypol is closely associated with the decrease in fertilization capacity. |
2000 |
Contraception |
pmid:11137075
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Matlin SA et al. |
(-)-Gossypol: an active male antifertility agent. |
1985 |
Contraception |
pmid:3987276
|
Sufi SB et al. |
Inhibition by (+) and (-) isomers of gossypol of testosterone release from mouse Leydig cells in vitro. |
1985 |
Contraception |
pmid:3987277
|
Wang Y et al. |
Antifertility effect of polyvinylpyrrolidone-gossypol and gossypol in male rats. |
1985 |
Contraception |
pmid:4092462
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Wu YM et al. |
Effects of gossypol on pituitary-ovarian endocrine function, ovulation and fertility in female hamsters. |
1981 |
Contraception |
pmid:6796329
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Wong PY et al. |
Lack of an effect of gossypol on the epididymis of the rat. |
1983 |
Contraception |
pmid:6851567
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Pearce S et al. |
The viability of mouse Leydig cells in vitro following incubation with gossypol. |
1985 |
Contraception |
pmid:4085245
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Gu Y and Anderson NO |
Effects of gossypol on the estrous cycle and ovarian weight in the rat. |
1985 |
Contraception |
pmid:4085249
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Anuja MN et al. |
Spermatotoxicity of a protein isolated from the root of Achyranthes aspera: a comparative study with gossypol. |
2010 |
Contraception |
pmid:20851234
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Coutinho EM |
Gossypol: a contraceptive for men. |
2002 |
Contraception |
pmid:12020773
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Han ML et al. |
Gossypol in the treatment of endometriosis and uterine myoma. |
1987 |
Contrib Gynecol Obstet |
pmid:3121251
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Efficient production of gossypol from hairy root cultures of cotton (Gossypium hirsutum L.). |
2009 |
Curr Pharm Biotechnol |
pmid:19751178
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Male contraception. |
2002 |
Curr Womens Health Rep |
pmid:12215306
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Inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. |
2008 |
Curr. Med. Chem. |
pmid:18220769
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2003 |
Curr. Med. Chem. |
pmid:12871134
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Gossypol: prototype of inhibitors targeted to dinucleotide folds. |
2000 |
Curr. Med. Chem. |
pmid:10702620
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Mechanism of drug and toxic actions of gossypol: focus on reactive oxygen species and electron transfer. |
2003 |
Curr. Med. Chem. |
pmid:14529461
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Bcl-2 inhibitors: emerging drugs in cancer therapy. |
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Occurrence of gossypol. |
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Curr. Sci. |
pmid:21007609
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High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions. |
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Diabetes |
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Dokl. Akad. Nauk SSSR |
pmid:1140070
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[Dependence of the protonophore and channel-forming capacity of gossypol on the pH]. |
1985 |
Dokl. Akad. Nauk SSSR |
pmid:2408838
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Gossypol, a polyphenolic aldehyde from cotton plant, interferes with swine granulosa cell function. |
2009 |
Domest. Anim. Endocrinol. |
pmid:19342192
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Subchronic oral administration of gossypol-acetic acid (GAA) alters the distribution and utilization of radioiron in male rats. |
1988 |
Drug Chem Toxicol |
pmid:3402348
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Tone JN and Jensen DR |
Radioiron utilization and gossypol acetic acid in male rats. |
1985 |
Drug Chem Toxicol |
pmid:4017900
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Lagerlöf RK and Tone JN |
The effect of gossypol acetic acid on female reproduction. |
1985 |
Drug Chem Toxicol |
pmid:4092619
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Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer. |
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Drug Des Devel Ther |
pmid:26089640
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Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway. |
2014 |
Drug Des Devel Ther |
pmid:25548514
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Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor. |
2014 |
Drug Des Devel Ther |
pmid:24872679
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Prospects for pharmacological male contraception. |
1994 |
Drugs |
pmid:7533693
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Wu D |
An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease. |
1989 |
Drugs |
pmid:2680434
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A review of the current status in male contraceptive studies. |
1983 |
East Afr Med J |
pmid:6354690
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Suzuki H et al. |
[Studies on naturally occurring toxic substances (III). Determination of gossypol in seed kernels of cotton plants by high performance liquid chromatography]. |
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pmid:3567428
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[Immunomodulating effect of the novel water-soluble gossypol derivative Mebavin in adjuvant arthritis]. |
2004 Mar-Apr |
Eksp Klin Farmakol |
pmid:15188763
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[Anti-inflammatory activity of the novel water soluble gossipol derivative mebavine]. |
2003 Nov-Dec |
Eksp Klin Farmakol |
pmid:14743712
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Colman N et al. |
Non-mutagenicity of gossypol in the Salmonella/mammalian-microsome plate assay. |
1979 |
Environ Mutagen |
pmid:399915
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Interactive effects of elevated CO2 and cotton cultivar on tri-trophic interaction of Gossypium hirsutum, Aphis gossyppii, and Propylaea japonica. |
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Environ. Entomol. |
pmid:18348793
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Effect of racemic, (+)- and (-)-gossypol on survival and development of Heliothis virescens larvae. |
2008 |
Environ. Entomol. |
pmid:19036185
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Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. |
1991 |
Environ. Mol. Mutagen. |
pmid:1915316
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Liang JC and Ye WS |
Clastogenicity of a male contraceptive, gossypol, in mammalian cell cultures with and without the metabolic activation by S9 mix. |
1985 |
Environ. Res. |
pmid:3967635
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Modulatory influence of tin-protoporphyrin on gossypol-induced alterations of heme oxygenase activity in male Wistar rats. |
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Proteinaceous diet inhibits gossypol-induced spermatotoxicity. |
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Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents. |
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Eur J Med Chem |
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Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant--gossypol. |
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Eur J Med Chem |
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