| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yuan J and Ching CB | Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae. | 2015 | Microb. Cell Fact. | pmid:25889168 |
| Yuan J and Ching CB | Combinatorial engineering of mevalonate pathway for improved amorpha-4,11-diene production in budding yeast. | 2014 | Biotechnol. Bioeng. | pmid:24122315 |
| Sun Z et al. | Identification of novel knockout targets for improving terpenoids biosynthesis in Saccharomyces cerevisiae. | 2014 | PLoS ONE | pmid:25386654 |
| Komori A et al. | Comparative functional analysis of CYP71AV1 natural variants reveals an important residue for the successive oxidation of amorpha-4,11-diene. | 2013 | FEBS Lett. | pmid:23246612 |
| Zhou K et al. | Optimization of amorphadiene synthesis in bacillus subtilis via transcriptional, translational, and media modulation. | 2013 | Biotechnol. Bioeng. | pmid:23483530 |
| Zou R et al. | Combinatorial engineering of 1-deoxy-D-xylulose 5-phosphate pathway using cross-lapping in vitro assembly (CLIVA) method. | 2013 | PLoS ONE | pmid:24223968 |
| Wang H et al. | Trichome-specific expression of the amorpha-4,11-diene 12-hydroxylase (cyp71av1) gene, encoding a key enzyme of artemisinin biosynthesis in Artemisia annua, as reported by a promoter-GUS fusion. | 2013 | Plant Mol. Biol. | pmid:23161198 |
| Chen X et al. | Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. | 2013 | PLoS ONE | pmid:24278153 |
| Dahl RH et al. | Engineering dynamic pathway regulation using stress-response promoters. | 2013 | Nat. Biotechnol. | pmid:24142050 |
| Shen J et al. | Improvement of amorpha-4,11-diene production by a yeast-conform variant of Vitreoscilla hemoglobin. | 2012 Mar-Apr | Z. Naturforsch., C, J. Biosci. | pmid:22624336 |
| Shimane M et al. | Mevalonate-dependent enzymatic synthesis of amorphadiene driven by an ATP-regeneration system using polyphosphate kinase. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878192 |
| Zheng Z et al. | Engineering Escherichia coli for succinate production from hemicellulose via consolidated bioprocessing. | 2012 | Microb. Cell Fact. | pmid:22455836 |
| Westfall PJ et al. | Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22247290 |
| Zhang Y et al. | The production of artemisinin precursors in tobacco. | 2011 | Plant Biotechnol. J. | pmid:20723135 |
| Redding-Johanson AM et al. | Targeted proteomics for metabolic pathway optimization: application to terpene production. | 2011 | Metab. Eng. | pmid:21215324 |
| Ma SM et al. | Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. | 2011 | Metab. Eng. | pmid:21810477 |
| Wu T et al. | [Biosynthesis of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli through introducing mevalonate pathway]. | 2011 | Sheng Wu Gong Cheng Xue Bao | pmid:22016988 |
| Olofsson L et al. | Relative expression of genes of terpene metabolism in different tissues of Artemisia annua L. | 2011 | BMC Plant Biol. | pmid:21388533 |
| Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
| Cankar K et al. | A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. | 2011 | FEBS Lett. | pmid:21115006 |
| Peralta-Yahya PP et al. | Identification and microbial production of a terpene-based advanced biofuel. | 2011 | Nat Commun | pmid:21952217 |
| Misawa N | Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. | 2011 | Mar Drugs | pmid:21673887 |
| Wen W and Yu R | Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. | 2011 | Pharmacogn Rev | pmid:22279377 |
| Farhi M et al. | Generation of the potent anti-malarial drug artemisinin in tobacco. | 2011 | Nat. Biotechnol. | pmid:22158354 |
| Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
| Guantai E and Chibale K | How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials? | 2011 | Malar. J. | pmid:21411013 |
| Gao H et al. | Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites. | 2010 | Protein Cell | pmid:21203934 |
| Suthers PF et al. | Improved computational performance of MFA using elementary metabolite units and flux coupling. | 2010 | Metab. Eng. | pmid:19837183 |
| Komatsu M et al. | Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20133795 |
| Arsenault PR et al. | Reproductive development modulates gene expression and metabolite levels with possible feedback inhibition of artemisinin in Artemisia annua. | 2010 | Plant Physiol. | pmid:20724645 |
| Mannan A et al. | Survey of artemisinin production by diverse Artemisia species in northern Pakistan. | 2010 | Malar. J. | pmid:21047440 |
| van Herpen TW et al. | Nicotiana benthamiana as a production platform for artemisinin precursors. | 2010 | PLoS ONE | pmid:21151979 |
| Schramek N et al. | Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study. | 2010 | Phytochemistry | pmid:19932496 |
| Sleight SC et al. | Designing and engineering evolutionary robust genetic circuits. | 2010 | J Biol Eng | pmid:21040586 |
| Dietrich JA et al. | A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3). | 2009 | ACS Chem. Biol. | pmid:19271725 |
| Kong JQ et al. | The improvement of amorpha-4,11-diene production by a yeast-conform variant. | 2009 | J. Appl. Microbiol. | pmid:19191957 |
| Kong JQ et al. | [Production of amorpha-4,11-diene in engineered yeasts]. | 2009 | Yao Xue Xue Bao | pmid:21355330 |
| Anthony JR et al. | Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. | 2009 | Metab. Eng. | pmid:18775787 |
| Skerker JM et al. | Evolution, ecology and the engineered organism: lessons for synthetic biology. | 2009 | Genome Biol. | pmid:19941672 |
| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Castaño-Cerezo S et al. | An insight into the role of phosphotransacetylase (pta) and the acetate/acetyl-CoA node in Escherichia coli. | 2009 | Microb. Cell Fact. | pmid:19852855 |
| Michalodimitrakis K and Isalan M | Engineering prokaryotic gene circuits. | 2009 | FEMS Microbiol. Rev. | pmid:19016883 |
| Ma D et al. | Isolation and characterization of AaWRKY1, an Artemisia annua transcription factor that regulates the amorpha-4,11-diene synthase gene, a key gene of artemisinin biosynthesis. | 2009 | Plant Cell Physiol. | pmid:19880398 |
| Ro DK et al. | Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. | 2008 | BMC Biotechnol. | pmid:18983675 |
| Chang Y et al. | Identification of optimal measurement sets for complete flux elucidation in metabolic flux analysis experiments. | 2008 | Biotechnol. Bioeng. | pmid:18553391 |
| Zhang Y et al. | The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua. | 2008 | J. Biol. Chem. | pmid:18495659 |
| Zeng Q et al. | Production of artemisinin by genetically-modified microbes. | 2008 | Biotechnol. Lett. | pmid:18008167 |
| Huang B et al. | Heterologous production of secondary metabolites as pharmaceuticals in Saccharomyces cerevisiae. | 2008 | Biotechnol. Lett. | pmid:18512022 |
| Pscheidt B and Glieder A | Yeast cell factories for fine chemical and API production. | 2008 | Microb. Cell Fact. | pmid:18684335 |
| Suthers PF et al. | Metabolic flux elucidation for large-scale models using 13C labeled isotopes. | 2007 Sep-Nov | Metab. Eng. | pmid:17632026 |
| Kong JQ et al. | [Increase of copy number of HMG-CoA reductase and FPP synthase genes improves the amorpha4,11-diene production in engineered yeast]. | 2007 | Yao Xue Xue Bao | pmid:18338647 |
| Covello PS et al. | Functional genomics and the biosynthesis of artemisinin. | 2007 | Phytochemistry | pmid:17399751 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Serrano L | Synthetic biology: promises and challenges. | 2007 | Mol. Syst. Biol. | pmid:18091727 |
| Teoh KH et al. | Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin. | 2006 | FEBS Lett. | pmid:16458889 |
| Newman JD et al. | High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli. | 2006 | Biotechnol. Bioeng. | pmid:16878333 |
| Lindahl AL et al. | Production of the artemisinin precursor amorpha-4,11-diene by engineered Saccharomyces cerevisiae. | 2006 | Biotechnol. Lett. | pmid:16614895 |
| Kim SH et al. | Cyclization mechanism of amorpha-4,11-diene synthase, a key enzyme in artemisinin biosynthesis. | 2006 | J. Nat. Prod. | pmid:16724836 |
| Picaud S et al. | Amorpha-4,11-diene synthase: mechanism and stereochemistry of the enzymatic cyclization of farnesyl diphosphate. | 2006 | Arch. Biochem. Biophys. | pmid:16143293 |
| Ro DK et al. | Production of the antimalarial drug precursor artemisinic acid in engineered yeast. | 2006 | Nature | pmid:16612385 |
| Wu S et al. | Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants. | 2006 | Nat. Biotechnol. | pmid:17057703 |
| Wallaart TE et al. | Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin. | 2001 | Planta | pmid:11289612 |
| pmid: | ||||
| pmid:19664791 | ||||
| pmid:27933789 | ||||
| pmid:17438551 | ||||
| pmid:27273626 | ||||
| pmid:27930305 | ||||
| pmid:28520394 | ||||
| pmid:22565787 | ||||
| pmid:18651187 | ||||
| pmid:15797234 | ||||
| pmid:28526743 | ||||
| pmid:26804325 | ||||
| pmid:25715782 | ||||
| pmid:25058645 | ||||
| pmid:27673334 | ||||
| pmid:15678372 | ||||
| pmid:18203058 |
amorpha-4,11-diene
Amorpha-4,11-diene is a lipid of Prenol Lipids (PR) class. Amorpha-4,11-diene is associated with abnormalities such as abnormal fragmented structure. The associated genes with amorpha-4,11-diene are Synthetic Genes.
Cross Reference
Introduction
To understand associated biological information of amorpha-4,11-diene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with amorpha-4,11-diene?
amorpha-4,11-diene is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with amorpha-4,11-diene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with amorpha-4,11-diene?
There are no associated biomedical information in the current reference collection.
What functions are associated with amorpha-4,11-diene?
There are no associated biomedical information in the current reference collection.
What lipids are associated with amorpha-4,11-diene?
There are no associated biomedical information in the current reference collection.
What genes are associated with amorpha-4,11-diene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with amorpha-4,11-diene?
There are no associated biomedical information in the current reference collection.