MeSH term | MeSH ID | Detail |
---|---|---|
Brain Damage, Chronic | D001925 | 6 associated lipids |
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Dystonia | D004421 | 3 associated lipids |
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pristanic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Brain Damage, Chronic | D001925 | 6 associated lipids |
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Dystonia | D004421 | 3 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Harris HM et al. | Phytanic acid, pristanic acid, and very-long-chain fatty acid methyl esters measured simultaneously by capillary gas chromatography. | 1989 | Clin. Chem. | pmid:2702761 |
Poulos A et al. | Defective oxidation of pristanic acid by fibroblasts from patients with disorders in propionic acid metabolism. | 1990 | Clin. Genet. | pmid:2311265 |
ten Brink HJ et al. | Pristanic acid does not accumulate in peroxisomal acyl-CoA oxidase deficiency: evidence for a distinct peroxisomal pristanyl-CoA oxidase. | 1991 | J. Inherit. Metab. Dis. | pmid:1779614 |
Kase BF et al. | Separation of phytanic and pristanic acid by high-pressure liquid chromatography: application of the method. | 1991 | Anal. Biochem. | pmid:1888042 |
ten Brink HJ et al. | Pristanic acid and phytanic acid in plasma from patients with a single peroxisomal enzyme deficiency. | 1991 | J. Inherit. Metab. Dis. | pmid:1722861 |
ten Brink HJ et al. | Pristanic acid and phytanic acid in plasma from patients with peroxisomal disorders: stable isotope dilution analysis with electron capture negative ion mass fragmentography. | 1992 | J. Lipid Res. | pmid:1372637 |
Chow CW et al. | Autopsy findings in two siblings with infantile Refsum disease. | 1992 | Acta Neuropathol. | pmid:1373019 |
ten Brink HJ et al. | In vivo study of phytanic acid alpha-oxidation in classic Refsum's disease and chondrodysplasia punctata. | 1992 | Pediatr. Res. | pmid:1282700 |
Singh I et al. | Phytanic acid alpha-oxidation in human cultured skin fibroblasts. | 1992 | Biochim. Biophys. Acta | pmid:1463774 |
Wanders RJ et al. | Activation and oxidation of pristanic acid in rat liver: identification of a distinct, clofibrate non-inducible pristanoyl-CoA oxidase. | 1992 | Prog. Clin. Biol. Res. | pmid:1438370 |