MeSH term | MeSH ID | Detail |
---|---|---|
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pristanic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Busanello EN et al. | Disruption of oxidative phosphorylation and synaptic Na(+), K(+)-ATPase activity by pristanic acid in cerebellum of young rats. | 2014 | Life Sci. | pmid:24211616 |
Wright ME et al. | Serum phytanic and pristanic acid levels and prostate cancer risk in Finnish smokers. | 2014 | Cancer Med | pmid:25132681 |
Klein CJ et al. | Plasma fatty acids in premature infants with hyperbilirubinemia: before-and-after nutrition support with fish oil emulsion. | 2013 | Nutr Clin Pract | pmid:23319354 |
Busanello EN et al. | Experimental evidence that pristanic acid disrupts mitochondrial homeostasis in brain of young rats. | 2012 | J. Neurosci. Res. | pmid:22183871 |
Mamedov IS et al. | [The diagnostic of peroxisomic diseases in children]. | 2012 | Klin. Lab. Diagn. | pmid:22712285 |
McMillan HJ et al. | Specific combination of compound heterozygous mutations in 17β-hydroxysteroid dehydrogenase type 4 (HSD17B4) defines a new subtype of D-bifunctional protein deficiency. | 2012 | Orphanet J Rare Dis | pmid:23181892 |
Rizzo WB | The role of fatty aldehyde dehydrogenase in epidermal structure and function. | 2011 | Dermatoendocrinol | pmid:21695018 |
Terre'Blanche G et al. | Treatment of an adrenomyeloneuropathy patient with Lorenzo's oil and supplementation with docosahexaenoic acid--a case report. | 2011 | Lipids Health Dis | pmid:21871076 |
Steinberg D | Chance and serendipity in science: two examples from my own career. | 2011 | J. Biol. Chem. | pmid:21908608 |
Leipnitz G et al. | Pristanic acid promotes oxidative stress in brain cortex of young rats: a possible pathophysiological mechanism for brain damage in peroxisomal disorders. | 2011 | Brain Res. | pmid:21241675 |