MeSH term | MeSH ID | Detail |
---|---|---|
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pristanic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Retinitis Pigmentosa | D012174 | 6 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Peroxisomal Disorders | D018901 | 5 associated lipids |
Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Singh I et al. | Phytanic acid alpha-oxidation in human cultured skin fibroblasts. | 1992 | Biochim. Biophys. Acta | pmid:1463774 |
Johnson DW et al. | Measurement of plasma pristanic, phytanic and very long chain fatty acids by liquid chromatography-electrospray tandem mass spectrometry for the diagnosis of peroxisomal disorders. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:14630371 |
Wanders RJ et al. | Molecular analysis of disorders of peroxisomal beta-oxidation. | 1992 | Prog. Clin. Biol. Res. | pmid:1438395 |
Wanders RJ et al. | Activation and oxidation of pristanic acid in rat liver: identification of a distinct, clofibrate non-inducible pristanoyl-CoA oxidase. | 1992 | Prog. Clin. Biol. Res. | pmid:1438370 |
ten Brink HJ et al. | Phytanic acid alpha-oxidation: accumulation of 2-hydroxyphytanic acid and absence of 2-oxophytanic acid in plasma from patients with peroxisomal disorders. | 1992 | J. Lipid Res. | pmid:1385561 |
Chow CW et al. | Autopsy findings in two siblings with infantile Refsum disease. | 1992 | Acta Neuropathol. | pmid:1373019 |
ten Brink HJ et al. | Pristanic acid and phytanic acid in plasma from patients with peroxisomal disorders: stable isotope dilution analysis with electron capture negative ion mass fragmentography. | 1992 | J. Lipid Res. | pmid:1372637 |
Mobley JA et al. | Branched fatty acids in dairy and beef products markedly enhance alpha-methylacyl-CoA racemase expression in prostate cancer cells in vitro. | 2003 | Cancer Epidemiol. Biomarkers Prev. | pmid:12917210 |
Straube R et al. | Membrane differential filtration is safe and effective for the long-term treatment of Refsum syndrome--an update of treatment modalities and pathophysiological cognition. | 2003 | Transfus. Apher. Sci. | pmid:12877898 |
ten Brink HJ et al. | In vivo study of phytanic acid alpha-oxidation in classic Refsum's disease and chondrodysplasia punctata. | 1992 | Pediatr. Res. | pmid:1282700 |