| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Retinitis Pigmentosa | D012174 | 6 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Dystonia | D004421 | 3 associated lipids |
Pristanic acid
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
Cross Reference
Introduction
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pristanic acid?
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pristanic acid
PubChem Associated disorders and diseases
What pathways are associated with Pristanic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pristanic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pristanic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Pristanic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Pristanic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Pristanic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pristanic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| ten Brink HJ et al. | Pristanic acid and phytanic acid in plasma from patients with a single peroxisomal enzyme deficiency. | 1991 | J. Inherit. Metab. Dis. | pmid:1722861 |
| Dahlgren J et al. | Cluster of systemic lupus erythematosus (SLE) associated with an oil field waste site: a cross sectional study. | 2007 | Environ Health | pmid:17316448 |
| Villarroya F et al. | PPARs in the Control of Uncoupling Proteins Gene Expression. | 2007 | PPAR Res | pmid:17389766 |
| Fraccascia P et al. | Presence of thiamine pyrophosphate in mammalian peroxisomes. | 2007 | BMC Biochem. | pmid:17596263 |
| Westin MA et al. | Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse. | 2007 | J. Biol. Chem. | pmid:17613526 |
| ten Brink HJ et al. | Pristanic acid does not accumulate in peroxisomal acyl-CoA oxidase deficiency: evidence for a distinct peroxisomal pristanyl-CoA oxidase. | 1991 | J. Inherit. Metab. Dis. | pmid:1779614 |
| pmid:17956234 | ||||
| pmid:17956235 | ||||
| Thompson SA et al. | Relapsing encephalopathy in a patient with alpha-methylacyl-CoA racemase deficiency. | 2008 | J. Neurol. Neurosurg. Psychiatr. | pmid:18032455 |
| pmid:18077198 | ||||
| Schrader M and Fahimi HD | The peroxisome: still a mysterious organelle. | 2008 | Histochem. Cell Biol. | pmid:18274771 |
| Al-Dirbashi OY et al. | Rapid UPLC-MS/MS method for routine analysis of plasma pristanic, phytanic, and very long chain fatty acid markers of peroxisomal disorders. | 2008 | J. Lipid Res. | pmid:18441019 |
| pmid:18536048 | ||||
| Zheng BS et al. | Arabidopsis sterol carrier protein-2 is required for normal development of seeds and seedlings. | 2008 | J. Exp. Bot. | pmid:18687588 |
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| pmid:19005174 | ||||
| Krause C et al. | Rational diagnostic strategy for Zellweger syndrome spectrum patients. | 2009 | Eur. J. Hum. Genet. | pmid:19142205 |
| Mackie JT et al. | Phytol-induced hepatotoxicity in mice. | 2009 | Toxicol Pathol | pmid:19188468 |
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| GarcÃa-Rojas P et al. | Induction of peroxisomal proliferator-activated receptor gamma and peroxisomal proliferator-activated receptor gamma coactivator 1 by unsaturated fatty acids, retinoic acid, and carotenoids in preadipocytes obtained from bovine white adipose tissue1,2. | 2010 | J. Anim. Sci. | pmid:20154154 |
| pmid:20388135 | ||||
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| Wanders RJ et al. | The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. | 2010 | J. Inherit. Metab. Dis. | pmid:20490924 |
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| Smith EH et al. | An adult onset case of alpha-methyl-acyl-CoA racemase deficiency. | 2010 | J. Inherit. Metab. Dis. | pmid:20821052 |
| Astarita G et al. | Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. | 2010 | PLoS ONE | pmid:20838618 |
| Kapina V et al. | Relapsing rhabdomyolysis due to peroxisomal alpha-methylacyl-coa racemase deficiency. | 2010 | Neurology | pmid:20921516 |
| Watkins PA et al. | Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions. | 2010 | BMC Physiol. | pmid:20932325 |
| Leipnitz G et al. | Pristanic acid promotes oxidative stress in brain cortex of young rats: a possible pathophysiological mechanism for brain damage in peroxisomal disorders. | 2011 | Brain Res. | pmid:21241675 |
| Sevin C et al. | Autosomal recessive cerebellar ataxia caused by mutations in the PEX2 gene. | 2011 | Orphanet J Rare Dis | pmid:21392394 |
| Busanello EN et al. | Neurochemical evidence that pristanic acid impairs energy production and inhibits synaptic Na(+), K(+)-ATPase activity in brain of young rats. | 2011 | Neurochem. Res. | pmid:21445584 |
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| Kruska N and Reiser G | Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. | 2011 | Neurobiol. Dis. | pmid:21570468 |
| Kou J et al. | Peroxisomal alterations in Alzheimer's disease. | 2011 | Acta Neuropathol. | pmid:21594711 |
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| Thompson SA et al. | Relapsing encephalopathy in a patient with α-methylacyl-CoA racemase deficiency. | 2009 | BMJ Case Rep | pmid:21686617 |
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| Poulos A et al. | Defective oxidation of pristanic acid by fibroblasts from patients with disorders in propionic acid metabolism. | 1990 | Clin. Genet. | pmid:2311265 |
| McMillan HJ et al. | Specific combination of compound heterozygous mutations in 17β-hydroxysteroid dehydrogenase type 4 (HSD17B4) defines a new subtype of D-bifunctional protein deficiency. | 2012 | Orphanet J Rare Dis | pmid:23181892 |
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| Busanello EN et al. | Disruption of oxidative phosphorylation and synaptic Na(+), K(+)-ATPase activity by pristanic acid in cerebellum of young rats. | 2014 | Life Sci. | pmid:24211616 |
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| Wright ME et al. | Serum phytanic and pristanic acid levels and prostate cancer risk in Finnish smokers. | 2014 | Cancer Med | pmid:25132681 |