| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Peroxisomal Disorders | D018901 | 5 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
Pristanic acid
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
Cross Reference
Introduction
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pristanic acid?
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pristanic acid
PubChem Associated disorders and diseases
What pathways are associated with Pristanic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
- J. Lipid Res. (3)
- J. Neurol. Neurosurg. Psychiatr. (1)
- Cancer Epidemiol. Biomarkers Prev. (1)
- Others (1)
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pristanic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pristanic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pristanic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pristanic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Pristanic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pristanic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:25168382 | ||||
| pmid:25172216 | ||||
| pmid:26947510 | ||||
| Harris HM et al. | Phytanic acid, pristanic acid, and very-long-chain fatty acid methyl esters measured simultaneously by capillary gas chromatography. | 1989 | Clin. Chem. | pmid:2702761 |
| pmid:27189059 | ||||
| pmid:28566232 | ||||
| pmid:28629946 | ||||
| Singh I et al. | Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes. | 1993 | J. Lipid Res. | pmid:7504046 |
| Jakobs BS and Wanders RJ | Fatty acid beta-oxidation in peroxisomes and mitochondria: the first, unequivocal evidence for the involvement of carnitine in shuttling propionyl-CoA from peroxisomes to mitochondria. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7654220 |
| Schmitt K et al. | [Zellweger syndrome, neonatal adrenoleukodystrophy or infantile Refsum's disease in a case with generalized peroxisome defect?]. | 1993 | Wien. Klin. Wochenschr. | pmid:7687405 |
| Pahan K et al. | Phytanic acid alpha-oxidation in rat liver mitochondria. | 1994 | Biochim. Biophys. Acta | pmid:7803482 |
| Singh H and Poulos A | Substrate specificity of rat liver mitochondrial carnitine palmitoyl transferase I: evidence against alpha-oxidation of phytanic acid in rat liver mitochondria. | 1995 | FEBS Lett. | pmid:7867794 |
| Wanders RJ et al. | Clinical and biochemical characteristics of peroxisomal disorders: an update. | 1994 | Eur. J. Pediatr. | pmid:7957386 |
| ten Brink HJ et al. | Heterogeneity in di/trihydroxycholestanoic acidaemia. | 1994 | Ann. Clin. Biochem. | pmid:8060102 |
| Singh H et al. | Peroxisomal beta-oxidation of branched chain fatty acids in rat liver. Evidence that carnitine palmitoyltransferase I prevents transport of branched chain fatty acids into mitochondria. | 1994 | J. Biol. Chem. | pmid:8144536 |
| ten Brink HJ et al. | Diagnosis of peroxisomal disorders by analysis of phytanic and pristanic acids in stored blood spots collected at neonatal screening. | 1993 | Clin. Chem. | pmid:8375069 |
| Paton BC et al. | Oxidation of pristanic acid in fibroblasts and its application to the diagnosis of peroxisomal beta-oxidation defects. | 1996 | J. Clin. Invest. | pmid:8609223 |
| Jakobs BS and Wanders RJ | Impaired peroxisomal fatty acid oxidation in human skin fibroblasts with a mitochondrial acylcarnitine/carnitine translocase deficiency. | 1996 | J. Inherit. Metab. Dis. | pmid:8739961 |
| Kase BF and Björkhem I | Studies on the degradation of [U-3H]-phytanic acid and [U-3H]-pristanic acid in cultured fibroblasts from children with peroxisomal disorders. | 1996 | Scand. J. Clin. Lab. Invest. | pmid:8761525 |
| Clayton PT et al. | Ataxia associated with increased plasma concentrations of pristanic acid, phytanic acid and C27 bile acids but normal fibroblast branched-chain fatty acid oxidation. | 1996 | J. Inherit. Metab. Dis. | pmid:8982949 |
| Paton BC et al. | Biochemical findings in a series of Australian patients with isolated defects in peroxisomal beta-oxidation. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993614 |
| Mota CR et al. | Rhizomelic chondrodysplasia punctata-like phenotype in a newborn male with normal peroxisomal function. | 1997 | J Pediatr Orthop B | pmid:9039662 |
| Wanders RJ et al. | Measurement of peroxisomal fatty acid beta-oxidation in cultured human skin fibroblasts. | 1995 | J. Inherit. Metab. Dis. | pmid:9053546 |
| Verhoeven NM et al. | Pre- and postnatal diagnosis of peroxisomal disorders using stable-isotope dilution gas chromatography--mass spectrometry. | 1995 | J. Inherit. Metab. Dis. | pmid:9053555 |
| Dacremont G et al. | Measurement of very long-chain fatty acids, phytanic and pristanic acid in plasma and cultured fibroblasts by gas chromatography. | 1995 | J. Inherit. Metab. Dis. | pmid:9053557 |
| van Grunsven EG et al. | Complementation analysis of fibroblasts from peroxisomal fatty acid oxidation deficient patients shows high frequency of bifunctional enzyme deficiency plus intragenic complementation: unequivocal evidence for differential defects in the same enzyme protein. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9196058 |
| Dieuaide-Noubhani M et al. | Evidence that multifunctional protein 2, and not multifunctional protein 1, is involved in the peroxisomal beta-oxidation of pristanic acid. | 1997 | Biochem. J. | pmid:9230115 |
| van Grunsven EG and Wanders RJ | Genetic heterogeneity in patients with a disorder of peroxisomal beta-oxidation: a complementation study based on pristanic acid beta-oxidation suggesting different enzyme defects. | 1997 | J. Inherit. Metab. Dis. | pmid:9266375 |
| Verhoeven NM et al. | Formation of 2,3-pristenic acid and 3-hydroxypristanic acid from pristanic acid in human liver. | 1997 | J. Inherit. Metab. Dis. | pmid:9266376 |
| Verhoeven NM et al. | Resolution of the phytanic acid alpha-oxidation pathway: identification of pristanal as product of the decarboxylation of 2-hydroxyphytanoyl-CoA. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9266824 |
| Verhoeven NM et al. | Phytanic acid alpha-oxidation: decarboxylation of 2-hydroxyphytanoyl-CoA to pristanic acid in human liver. | 1997 | J. Lipid Res. | pmid:9374128 |
| Verhoeven NM et al. | Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts. | 1998 | J. Lipid Res. | pmid:9469587 |
| Verhoeven NM et al. | Pristanic acid beta-oxidation in peroxisomal disorders: studies in cultured human fibroblasts. | 1998 | Biochim. Biophys. Acta | pmid:9555092 |
| Sequeira JS et al. | Niemann-Pick disease type C and defective peroxisomal beta-oxidation of branched-chain substrates. | 1998 | J. Inherit. Metab. Dis. | pmid:9584266 |
| Verhoeven NM et al. | Involvement of microsomal fatty aldehyde dehydrogenase in the alpha-oxidation of phytanic acid. | 1998 | FEBS Lett. | pmid:9662422 |
| Wanders RJ et al. | Identification of the newly discovered 58 kDa peroxisomal thiolase SCPx as the main thiolase involved in both pristanic acid and trihydroxycholestanoic acid oxidation: implications for peroxisomal beta-oxidation disorders. | 1998 | J. Inherit. Metab. Dis. | pmid:9686381 |
| Vreken P et al. | Rapid stable isotope dilution analysis of very-long-chain fatty acids, pristanic acid and phytanic acid using gas chromatography-electron impact mass spectrometry. | 1998 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9746242 |
| Verhoeven NM et al. | The metabolism of phytanic acid and pristanic acid in man: a review. | 1998 | J. Inherit. Metab. Dis. | pmid:9819701 |
| Verhoeven NM et al. | Studies on the oxidation of phytanic acid and pristanic acid in human fibroblasts by acylcarnitine analysis. | 1998 | J. Inherit. Metab. Dis. | pmid:9819705 |
| van Grunsven EG et al. | Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis. | 1999 | Am. J. Hum. Genet. | pmid:9915948 |
| Verhoeven NM et al. | Analysis of pristanic acid beta-oxidation intermediates in plasma from healthy controls and patients affected with peroxisomal disorders by stable isotope dilution gas chromatography mass spectrometry. | 1999 | J. Lipid Res. | pmid:9925655 |