| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Peroxisomal Disorders | D018901 | 5 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
Pristanic acid
Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.
Cross Reference
Introduction
To understand associated biological information of Pristanic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pristanic acid?
Pristanic acid is suspected in Peroxisomal Disorders, Refsum Disease, Protein Deficiency, Retinitis Pigmentosa, Enzyme Deficiency, Hereditary Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pristanic acid
PubChem Associated disorders and diseases
What pathways are associated with Pristanic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pristanic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pristanic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pristanic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Pristanic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Pristanic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Pristanic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pristanic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Idel S et al. | Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells. | 2002 | J. Biol. Chem. | pmid:12368296 |
| McLean BN et al. | A new defect of peroxisomal function involving pristanic acid: a case report. | 2002 | J. Neurol. Neurosurg. Psychiatr. | pmid:11861706 |
| Ofman R et al. | Demonstration of dimethylnonanoyl-CoA thioesterase activity in rat liver peroxisomes followed by purification and molecular cloning of the thioesterase involved. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11785945 |
| Gootjes J et al. | Biochemical markers predicting survival in peroxisome biogenesis disorders. | 2002 | Neurology | pmid:12473763 |
| Ferdinandusse S et al. | Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency. | 2001 | J. Lipid Res. | pmid:11160375 |
| Van Veldhoven PP et al. | Fibroblast studies documenting a case of peroxisomal 2-methylacyl-CoA racemase deficiency: possible link between racemase deficiency and malabsorption and vitamin K deficiency. | 2001 | Eur. J. Clin. Invest. | pmid:11473573 |
| Verhoeven NM and Jakobs C | Human metabolism of phytanic acid and pristanic acid. | 2001 | Prog. Lipid Res. | pmid:11591435 |
| Jansen GA et al. | Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11341778 |
| Wanders RJ et al. | Lipid metabolism in peroxisomes: enzymology, functions and dysfunctions of the fatty acid alpha- and beta-oxidation systems in humans. | 2000 | Biochem. Soc. Trans. | pmid:10816116 |
| Zomer AW et al. | Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor alpha. | 2000 | J. Lipid Res. | pmid:11060349 |
| Ferdinandusse S et al. | Subcellular localization and physiological role of alpha-methylacyl-CoA racemase. | 2000 | J. Lipid Res. | pmid:11060359 |
| Steinberg SJ et al. | Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198260 |
| van Grunsven EG et al. | Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis. | 1999 | Am. J. Hum. Genet. | pmid:9915948 |
| Ferdinandusse S et al. | Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta-oxidation of branched-chain fatty acids. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10486279 |
| Verhoeven NM et al. | Analysis of pristanic acid beta-oxidation intermediates in plasma from healthy controls and patients affected with peroxisomal disorders by stable isotope dilution gas chromatography mass spectrometry. | 1999 | J. Lipid Res. | pmid:9925655 |
| Verhoeven NM et al. | Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts. | 1998 | J. Lipid Res. | pmid:9469587 |
| Sequeira JS et al. | Niemann-Pick disease type C and defective peroxisomal beta-oxidation of branched-chain substrates. | 1998 | J. Inherit. Metab. Dis. | pmid:9584266 |
| Verhoeven NM et al. | The metabolism of phytanic acid and pristanic acid in man: a review. | 1998 | J. Inherit. Metab. Dis. | pmid:9819701 |
| Verhoeven NM et al. | Studies on the oxidation of phytanic acid and pristanic acid in human fibroblasts by acylcarnitine analysis. | 1998 | J. Inherit. Metab. Dis. | pmid:9819705 |
| Verhoeven NM et al. | Involvement of microsomal fatty aldehyde dehydrogenase in the alpha-oxidation of phytanic acid. | 1998 | FEBS Lett. | pmid:9662422 |