forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

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Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

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Authors Title Published Journal PubMed Link
Meents JE et al. Sensitization of TRPA1 by Protein Kinase A. 2017 PLoS ONE pmid:28076424
Shi R et al. Naringenin Regulates CFTR Activation and Expression in Airway Epithelial Cells. 2017 Cell. Physiol. Biochem. pmid:29179179
Cai P et al. BMP4 inhibits PDGF-induced proliferation and collagen synthesis via PKA-mediated inhibition of calpain-2 in pulmonary artery smooth muscle cells. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28235949
Kruglov E et al. Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP. 2017 Biochem. Biophys. Res. Commun. pmid:28327356
Gerarduzzi C et al. Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration. 2017 J. Cell. Physiol. pmid:27137893
Chen G et al. AMP010014A09 in Sus Scrofa Encodes an Analog of G Protein-Coupled Receptor 109A, Which Mediates the Anti-Inflammatory Effects of Beta-Hydroxybutyric Acid. 2017 Cell. Physiol. Biochem. pmid:28715817
Lu N et al. Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. 2017 J. Steroid Biochem. Mol. Biol. pmid:28602959
Takayama Y et al. Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors. 2017 FEBS Lett. pmid:28129669
Malty RH et al. Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. 2016 J Neuroinflammation pmid:27400965
Ignea C et al. Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities. 2016 Microb. Cell Fact. pmid:26920948