Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hirabayashi M et al. | Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. | 2014 | Stem Cells Dev. | pmid:24010570 |
Paldino E et al. | Induction of dopaminergic neurons from human Wharton's jelly mesenchymal stem cell by forskolin. | 2014 | J. Cell. Physiol. | pmid:23893793 |
Rojas-Charry L et al. | Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. | 2014 | Neurotoxicology | pmid:24792327 |
Ikari A et al. | Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells. | 2014 | Biochim. Biophys. Acta | pmid:24907662 |
Razmi A et al. | Cyclic AMP pathway modifies memory through neural cell adhesion molecule alterations in the rat hippocampus. | 2014 | Acta Med Iran | pmid:24901853 |
Nwachukwu JC et al. | Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. | 2014 | Elife | pmid:24771768 |
Shirasu M et al. | Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors. | 2014 | Neuron | pmid:24361078 |
Mardones P et al. | Cyclic AMP and alkaline pH downregulate carbonic anhydrase 2 in mouse fibroblasts. | 2014 | Biochim. Biophys. Acta | pmid:24361611 |
Cheng X et al. | Generation and characterization of gsuα:EGFP transgenic zebrafish for evaluating endocrine-disrupting effects. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24747804 |
Li X et al. | cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and mitochondrial fusion. | 2014 | PLoS ONE | pmid:24642777 |