Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Koutsogiannaki S et al. | Oxidative stress parameters induced by exposure to either cadmium or 17β-estradiol on Mytilus galloprovincialis hemocytes. The role of signaling molecules. | 2014 | Aquat. Toxicol. | pmid:24316436 |
Ogawa M et al. | Theophylline potentiates lipopolysaccharide-induced NO production in cultured astrocytes. | 2014 | Neurochem. Res. | pmid:24234846 |
Mori M et al. | Effect of ATP-binding cassette subfamily B member 1 on bovine blastocyst implantation. | 2014 | Theriogenology | pmid:24411494 |
DiRaddo JO et al. | A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. | 2014 | J. Pharmacol. Exp. Ther. | pmid:24659805 |
Marlar S et al. | Elevated cAMP increases aquaporin-3 plasma membrane diffusion. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:24452376 |
Vardjan N et al. | Dynamics of β-adrenergic/cAMP signaling and morphological changes in cultured astrocytes. | 2014 | Glia | pmid:24464905 |
Jin Y et al. | Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia. | 2014 | J. Neurochem. | pmid:24447140 |
Ding S et al. | [Regulation of aquaporin 3 protein expression in amnion epithelial cells through cAMP-PKA signal pathway]. | 2014 | Zhonghua Fu Chan Ke Za Zhi | pmid:24694916 |
Takarada-Iemata M et al. | Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury. | 2014 | J. Neurochem. | pmid:24697507 |
Sahmi F et al. | Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model. | 2014 | Gen. Comp. Endocrinol. | pmid:24556528 |
Felizola SJ et al. | PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues. | 2014 | J. Mol. Endocrinol. | pmid:24403568 |
Christ T et al. | Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25024212 |
Lingam G and Wong TY | Systemic medical management of diabetic retinopathy. | 2013 Oct-Dec | Middle East Afr J Ophthalmol | pmid:24339679 |
Winther CS et al. | Corticosteroid production in H295R cells during exposure to 3 endocrine disrupters analyzed with LC-MS/MS. | 2013 May-Jun | Int. J. Toxicol. | pmid:23616146 |
Nunes AR et al. | Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors. | 2013 | Respir Physiol Neurobiol | pmid:23727159 |
Cuppoletti J et al. | Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents. | 2013 | Cell Biochem. Biophys. | pmid:22918821 |
Xu C et al. | A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. | 2013 | Cell | pmid:24209627 |
Cottingham C et al. | Cross-talk from β-adrenergic receptors modulates α2A-adrenergic receptor endocytosis in sympathetic neurons via protein kinase A and spinophilin. | 2013 | J. Biol. Chem. | pmid:23965992 |
Franzellitti S and Fabbri E | Cyclic-AMP mediated regulation of ABCB mRNA expression in mussel haemocytes. | 2013 | PLoS ONE | pmid:23593491 |
Oerlecke I et al. | Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression. | 2013 | PLoS ONE | pmid:23349840 |