Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gerarduzzi C et al. | Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration. | 2017 | J. Cell. Physiol. | pmid:27137893 |
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Lu N et al. | Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:28602959 |
Takayama Y et al. | Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors. | 2017 | FEBS Lett. | pmid:28129669 |
Malty RH et al. | Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. | 2016 | J Neuroinflammation | pmid:27400965 |
Ignea C et al. | Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities. | 2016 | Microb. Cell Fact. | pmid:26920948 |