Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gerarduzzi C et al. | Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration. | 2017 | J. Cell. Physiol. | pmid:27137893 |
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Savard C et al. | Prevention of deoxynivalenol- and zearalenone-associated oxidative stress does not restore MA-10 Leydig cell functions. | 2016 | Toxicology | pmid:26783879 |
Kuhlmann FM et al. | Blood Group O-Dependent Cellular Responses to Cholera Toxin: Parallel Clinical and Epidemiological Links to Severe Cholera. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27162272 |
Malty RH et al. | Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. | 2016 | J Neuroinflammation | pmid:27400965 |
Koyama H et al. | Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells. | 2016 | Endocrinology | pmid:26671185 |
Ignea C et al. | Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities. | 2016 | Microb. Cell Fact. | pmid:26920948 |
Clark AA et al. | Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction. | 2016 | J. Leukoc. Biol. | pmid:27154353 |
Pinne M et al. | Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation. | 2016 | PLoS ONE | pmid:27732639 |
Li L et al. | Differential effects of lysophosphatidylcholine and ACh on muscarinic K(+),non-selective cation and Ca(2+) currents in guinea-pig atrial cells. | 2016 | Fukushima J Med Sci | pmid:26911304 |
Jones AR et al. | Extracellular Redox Regulation of Intracellular Reactive Oxygen Generation, Mitochondrial Function and Lipid Turnover in Cultured Human Adipocytes. | 2016 | PLoS ONE | pmid:27741233 |
Angel-Chavez LI et al. | Forskolin suppresses delayed-rectifier K+ currents and enhances spike frequency-dependent adaptation of sympathetic neurons. | 2015 | PLoS ONE | pmid:25962132 |
Shrestha K et al. | Regulation of ovulatory genes in bovine granulosa cells: lessons from siRNA silencing of PTGS2. | 2015 | Reproduction | pmid:25323036 |
Woodworth BA | Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiency. | 2015 | Laryngoscope | pmid:25946147 |