Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cao HH et al. | [Polymethoxylated flavonoids activate cystic fibrosis transmembrane conductance regulator chloride channel]. | 2015 | Sheng Li Xue Bao | pmid:25896054 |
Kawabata H et al. | A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. | 2015 | Exp. Hematol. | pmid:25633564 |
Yukiura H et al. | LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells. | 2015 | J. Cell. Sci. | pmid:26345369 |
Jóźwiak-Bębenista M et al. | The cyclic AMP effects and neuroprotective activities of PACAP and VIP in cultured astrocytes and neurons exposed to oxygen-glucose deprivation. | 2015 | Pharmacol Rep | pmid:25712659 |
Tao H et al. | Cyclic AMP prevents decrease of phosphorylated ezrin/radixin/moesin and chloride intracellular channel 5 expressions in injured podocytes. | 2015 | Clin. Exp. Nephrol. | pmid:25725994 |
Angel-Chavez LI et al. | Forskolin suppresses delayed-rectifier K+ currents and enhances spike frequency-dependent adaptation of sympathetic neurons. | 2015 | PLoS ONE | pmid:25962132 |
Fuccelli R et al. | The hydroxytyrosol-dependent increase of TNF-α in LPS-activated human monocytes is mediated by PGE2 and adenylate cyclase activation. | 2015 | Toxicol In Vitro | pmid:25866079 |
Mohan S et al. | Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. | 2015 | Neurotoxicology | pmid:25451967 |
Shrestha K et al. | Regulation of ovulatory genes in bovine granulosa cells: lessons from siRNA silencing of PTGS2. | 2015 | Reproduction | pmid:25323036 |
Pavan B et al. | Quercetin and quercetin-3-O-glucoside interact with different components of the cAMP signaling cascade in human retinal pigment epithelial cells. | 2015 | Life Sci. | pmid:25476834 |