forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Uterine Neoplasms D014594 18 associated lipids
Proteinuria D011507 30 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Cardiac Complexes, Premature D005117 6 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Cholestasis D002779 23 associated lipids
Fibrosis D005355 23 associated lipids
Thyroid Diseases D013959 8 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Ataxia D001259 20 associated lipids
Alcoholism D000437 27 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Brain Ischemia D002545 89 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Ischemia D007511 18 associated lipids
Colonic Diseases D003108 5 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Hyperthyroidism D006980 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Astrocytoma D001254 15 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Nasal Polyps D009298 26 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Leydig Cell Tumor D007984 6 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Erythema D004890 22 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Cholelithiasis D002769 16 associated lipids
Morphine Dependence D009021 9 associated lipids
Shock, Septic D012772 11 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Catalepsy D002375 30 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

Download all related citations
Per page 10 20 50 100 | Total 15624
Authors Title Published Journal PubMed Link
Meents JE et al. Sensitization of TRPA1 by Protein Kinase A. 2017 PLoS ONE pmid:28076424
Shi R et al. Naringenin Regulates CFTR Activation and Expression in Airway Epithelial Cells. 2017 Cell. Physiol. Biochem. pmid:29179179
Cai P et al. BMP4 inhibits PDGF-induced proliferation and collagen synthesis via PKA-mediated inhibition of calpain-2 in pulmonary artery smooth muscle cells. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28235949
Kruglov E et al. Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP. 2017 Biochem. Biophys. Res. Commun. pmid:28327356
Gerarduzzi C et al. Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration. 2017 J. Cell. Physiol. pmid:27137893
Chen G et al. AMP010014A09 in Sus Scrofa Encodes an Analog of G Protein-Coupled Receptor 109A, Which Mediates the Anti-Inflammatory Effects of Beta-Hydroxybutyric Acid. 2017 Cell. Physiol. Biochem. pmid:28715817
Lu N et al. Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. 2017 J. Steroid Biochem. Mol. Biol. pmid:28602959
Takayama Y et al. Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors. 2017 FEBS Lett. pmid:28129669
Malty RH et al. Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. 2016 J Neuroinflammation pmid:27400965
Ignea C et al. Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities. 2016 Microb. Cell Fact. pmid:26920948