forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Growth Disorders D006130 5 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Bradycardia D001919 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

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Authors Title Published Journal PubMed Link
Yukiura H et al. LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells. 2015 J. Cell. Sci. pmid:26345369
Jóźwiak-Bębenista M et al. The cyclic AMP effects and neuroprotective activities of PACAP and VIP in cultured astrocytes and neurons exposed to oxygen-glucose deprivation. 2015 Pharmacol Rep pmid:25712659
Mohan S et al. Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. 2015 Neurotoxicology pmid:25451967
Oztekin CV et al. Analysis of pomegranate juice components in rat corpora cavernosal relaxation. 2014 Mar-Apr Int. J. Impot. Res. pmid:23903908
Sunkara LT et al. Cyclic AMP synergizes with butyrate in promoting β-defensin 9 expression in chickens. 2014 Mol. Immunol. pmid:24141182
Chen L et al. Cyclic AMP enhances progesterone action in human myometrial cells. 2014 Mol. Cell. Endocrinol. pmid:24161591
Pateraki I et al. Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii. 2014 Plant Physiol. pmid:24481136
Cazabat L et al. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. 2014 Hum. Mol. Genet. pmid:24122441
Efird W et al. An evaluation of prophylactic treatments to prevent post traumatic joint stiffness. 2014 J. Orthop. Res. pmid:25073544
Hirabayashi M et al. Effect of leukemia inhibitory factor and forskolin on establishment of rat embryonic stem cell lines. 2014 J. Reprod. Dev. pmid:24317016