forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

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Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adrenal Cortex Neoplasms D000306 4 associated lipids
Albinism D000417 3 associated lipids
Alcoholism D000437 27 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anemia D000740 21 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

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Per page 10 20 50 100 | Total 15624
Authors Title Published Journal PubMed Link
Rose RD et al. Regulation of sheep oocyte maturation using cAMP modulators. 2013 Theriogenology pmid:23102843
Mu X et al. Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human umbilical vein endothelial cells. 2013 Free Radic. Res. pmid:23153326
Baillie GL et al. CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity. 2013 Mol. Pharmacol. pmid:23160940
Patching SG et al. Probing the contacts of a low-affinity substrate with a membrane-embedded transport protein using 1H-13C cross-polarisation magic-angle spinning solid-state NMR. 2013 Mol. Membr. Biol. pmid:23173920
Luo YL et al. Cellular mechanism underlying formaldehyde-stimulated Cl- secretion in rat airway epithelium. 2013 PLoS ONE pmid:23372735
Iancu CV et al. Crystal structure of a glucose/H+ symporter and its mechanism of action. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24127585
Wu YH et al. Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation. 2013 FASEB J. pmid:23580611
Pondugula SR et al. cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium. 2013 BMC Physiol. pmid:23537040
Galougahi KK et al. Protein kinase-dependent oxidative regulation of the cardiac Na+-K+ pump: evidence from in vivo and in vitro modulation of cell signalling. 2013 J. Physiol. (Lond.) pmid:23587884
Ringseis R et al. Sterol regulatory element-binding proteins are regulators of the NIS gene in thyroid cells. 2013 Mol. Endocrinol. pmid:23542164
Chen Y et al. MTA3 regulates CGB5 and Snail genes in trophoblast. 2013 Biochem. Biophys. Res. Commun. pmid:23510993
Bogum J et al. Small-molecule screening identifies modulators of aquaporin-2 trafficking. 2013 J. Am. Soc. Nephrol. pmid:23559583
Gantz SC et al. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor. 2013 Neuron pmid:23764286
Wang Q and Traynor JR Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells. 2013 Mol. Pharmacol. pmid:23197645
Robins GG et al. Rapid stimulation of human renal ENaC by cAMP in Xenopus laevis oocytes. 2013 J. Physiol. Biochem. pmid:23184731
Liang J et al. MicroRNA-29a-c decrease fasting blood glucose levels by negatively regulating hepatic gluconeogenesis. 2013 J. Hepatol. pmid:23111009
Jeong YM et al. Aglycone of Rh4 inhibits melanin synthesis in B16 melanoma cells: possible involvement of the protein kinase A pathway. 2013 Biosci. Biotechnol. Biochem. pmid:23291754
Sayasith K et al. Expression, regulation, and promoter activation of vanin-2 (VNN2) in bovine follicles prior to ovulation. 2013 Biol. Reprod. pmid:24006283
Di Prisco S et al. CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice. 2013 Neuropharmacology pmid:23958452
Toneatto J et al. Dynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation. 2013 J. Cell. Sci. pmid:24101724
Nakamura Y et al. FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1. 2013 Biochem. Biophys. Res. Commun. pmid:24129192
Wertheimer E et al. Compartmentalization of distinct cAMP signaling pathways in mammalian sperm. 2013 J. Biol. Chem. pmid:24129574
Su H et al. Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradation. 2013 Am. J. Physiol. Renal Physiol. pmid:24133116
Lu D et al. Increase in cellular cyclic AMP concentrations reverses the profibrogenic phenotype of cardiac myofibroblasts: a novel therapeutic approach for cardiac fibrosis. 2013 Mol. Pharmacol. pmid:24085841
Loo CS et al. Quantitative apical membrane proteomics reveals vasopressin-induced actin dynamics in collecting duct cells. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24085853
Hasegawa E et al. Effect of polyphenols on production of steroid hormones from human adrenocortical NCI-H295R cells. 2013 Biol. Pharm. Bull. pmid:23370353
Gomis J et al. Forskolin improves the cryosurvival of in vivo-derived porcine embryos at very early stages using two vitrification methods. 2013 Cryobiology pmid:23313786
Xia Y et al. Human SNF2L gene is regulated constitutively and inducibly in neural cells via a cAMP-response element. 2013 Yonsei Med. J. pmid:23549828
Kumar P and Song ZH Identification of raloxifene as a novel CB2 inverse agonist. 2013 Biochem. Biophys. Res. Commun. pmid:23611779
Shu L et al. Modulation of HERG K+ channels by chronic exposure to activators and inhibitors of PKA and PKC: actions independent of PKA and PKC phosphorylation. 2013 Cell. Physiol. Biochem. pmid:24356123
Palorini R et al. Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration. 2013 Oncogene pmid:22410778
Zeng HT et al. Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence. 2013 Hum. Reprod. pmid:23559189
Simon BR et al. Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors. 2013 J. Biol. Chem. pmid:24068707
Burdyga A et al. cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC. 2013 Biochim. Biophys. Acta pmid:23797058
McFadden SA et al. Glucose responsiveness in a novel adult-derived GnRH cell line, mHypoA-GnRH/GFP: involvement of AMP-activated protein kinase. 2013 Mol. Cell. Endocrinol. pmid:23835445
Liu ML et al. Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. 2013 Nat Commun pmid:23873306
Wu RY et al. Effect of cAMP on short-circuit current in isolated human ciliary body. 2013 Chin. Med. J. pmid:23876898
Murk K et al. The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. 2013 J. Cell. Sci. pmid:23843614
Rice S et al. Metformin inhibits follicle-stimulating hormone (FSH) action in human granulosa cells: relevance to polycystic ovary syndrome. 2013 J. Clin. Endocrinol. Metab. pmid:23846817
Zhao W et al. Dopamine receptors modulate cytotoxicity of natural killer cells via cAMP-PKA-CREB signaling pathway. 2013 PLoS ONE pmid:23799052
Wang X et al. Dehydrocostuslactone, a sesquiterpene lactone activates wild-type and ΔF508 mutant CFTR chloride channel. 2013 J Asian Nat Prod Res pmid:23799322
Emery AC et al. Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. 2013 Sci Signal pmid:23800469
Hauger RL et al. Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment. 2013 Regul. Pept. pmid:23820308
Cuello C et al. Effect of MEM vitamins and forskolin on embryo development and vitrification tolerance of in vitro-produced pig embryos. 2013 Anim. Reprod. Sci. pmid:23238049
Organ-Darling LE et al. Interactions between hERG and KCNQ1 α-subunits are mediated by their COOH termini and modulated by cAMP. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:23241319
Obara Y et al. Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells. 2013 Cell. Signal. pmid:23200849
Goto T et al. Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G. 2013 Cell. Signal. pmid:23201780
Yoshitake S et al. Concurrent modulation of extracellular levels of noradrenaline and cAMP during stress and by anxiogenic- or anxiolytic-like neuropeptides in the prefrontal cortex of awake rats. 2013 Neurochem. Int. pmid:23274451
Franz AK et al. Phenotypic screening with oleaginous microalgae reveals modulators of lipid productivity. 2013 ACS Chem. Biol. pmid:23521767
Danaher RJ et al. C-terminal trans-activation sub-region of VP16 is uniquely required for forskolin-induced herpes simplex virus type 1 reactivation from quiescently infected-PC12 cells but not for replication in neuronally differentiated-PC12 cells. 2013 J. Neurovirol. pmid:23192733