Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kawabata H et al. | A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. | 2015 | Exp. Hematol. | pmid:25633564 |
Jóźwiak-Bębenista M et al. | The cyclic AMP effects and neuroprotective activities of PACAP and VIP in cultured astrocytes and neurons exposed to oxygen-glucose deprivation. | 2015 | Pharmacol Rep | pmid:25712659 |
Tao H et al. | Cyclic AMP prevents decrease of phosphorylated ezrin/radixin/moesin and chloride intracellular channel 5 expressions in injured podocytes. | 2015 | Clin. Exp. Nephrol. | pmid:25725994 |
Oztekin CV et al. | Analysis of pomegranate juice components in rat corpora cavernosal relaxation. | 2014 Mar-Apr | Int. J. Impot. Res. | pmid:23903908 |
Koutsogiannaki S et al. | Oxidative stress parameters induced by exposure to either cadmium or 17β-estradiol on Mytilus galloprovincialis hemocytes. The role of signaling molecules. | 2014 | Aquat. Toxicol. | pmid:24316436 |
Boinot C et al. | Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing. | 2014 | J. Pharmacol. Exp. Ther. | pmid:24970923 |
Aflaki M et al. | Exchange protein directly activated by cAMP mediates slow delayed-rectifier current remodeling by sustained β-adrenergic activation in guinea pig hearts. | 2014 | Circ. Res. | pmid:24508724 |
DiRaddo JO et al. | A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. | 2014 | J. Pharmacol. Exp. Ther. | pmid:24659805 |
Marlar S et al. | Elevated cAMP increases aquaporin-3 plasma membrane diffusion. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:24452376 |
Sahmi F et al. | Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model. | 2014 | Gen. Comp. Endocrinol. | pmid:24556528 |