forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

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Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

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Authors Title Published Journal PubMed Link
Isensee J et al. Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons. 2014 J. Cell. Sci. pmid:24190886
Mango D et al. Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions. 2014 Neuropharmacology pmid:23973317
Hirabayashi M et al. Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. 2014 Stem Cells Dev. pmid:24010570
Rojas-Charry L et al. Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. 2014 Neurotoxicology pmid:24792327
Sunkara LT et al. Cyclic AMP synergizes with butyrate in promoting β-defensin 9 expression in chickens. 2014 Mol. Immunol. pmid:24141182
Chen L et al. Cyclic AMP enhances progesterone action in human myometrial cells. 2014 Mol. Cell. Endocrinol. pmid:24161591
Jeong JH et al. Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea. 2014 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:24793168
Chiarella SE et al. β₂-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. 2014 J. Clin. Invest. pmid:24865431
Ikari A et al. Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells. 2014 Biochim. Biophys. Acta pmid:24907662
Blake CB and Smith BN cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24990858
Pateraki I et al. Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii. 2014 Plant Physiol. pmid:24481136
Cazabat L et al. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. 2014 Hum. Mol. Genet. pmid:24122441
Marino GI and Kotsias BA Cystic fibrosis transmembrane regulator (CFTR) in human trophoblast BeWo cells and its relation to cell migration. 2014 Placenta pmid:24398014
Márquez L and Fuentes J In vitro characterization of acid secretion in the gilthead sea bream (Sparus aurata) stomach. 2014 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:24126049
Efird W et al. An evaluation of prophylactic treatments to prevent post traumatic joint stiffness. 2014 J. Orthop. Res. pmid:25073544
Yasuo S et al. 2-Arachidonoyl glycerol sensitizes the pars distalis and enhances forskolin-stimulated prolactin secretion in Syrian hamsters. 2014 Chronobiol. Int. pmid:24200164
Vasin A et al. Synapsin regulates activity-dependent outgrowth of synaptic boutons at the Drosophila neuromuscular junction. 2014 J. Neurosci. pmid:25100589
Wang Q et al. Caffeine accelerates recovery from general anesthesia. 2014 J. Neurophysiol. pmid:24375022
Hirabayashi M et al. Effect of leukemia inhibitory factor and forskolin on establishment of rat embryonic stem cell lines. 2014 J. Reprod. Dev. pmid:24317016
Sun H et al. Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion. 2014 Biomed Res Int pmid:24818160