forskolin

Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with forskolin?

forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with forskolin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 207

PubChem Associated disorders and diseases

What pathways are associated with forskolin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with forskolin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with forskolin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with forskolin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with forskolin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with forskolin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with forskolin

Download all related citations
Per page 10 20 50 100 | Total 15624
Authors Title Published Journal PubMed Link
Rose RD et al. Regulation of sheep oocyte maturation using cAMP modulators. 2013 Theriogenology pmid:23102843
Iancu CV et al. Crystal structure of a glucose/H+ symporter and its mechanism of action. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24127585
Wu YH et al. Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation. 2013 FASEB J. pmid:23580611
Pondugula SR et al. cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium. 2013 BMC Physiol. pmid:23537040
Zelarayán LI et al. Involvement of G protein and purines in Rhinella arenarum oocyte maturation. 2013 Zygote pmid:22300948
Seifert R A door opener for future research: agonist-induced β3-adrenoceptor desensitization in HEK cells but not CHO cells. 2013 Naunyn Schmiedebergs Arch. Pharmacol. pmid:23756577
Michel-Reher MB and Michel MC Agonist-induced desensitization of human β3-adrenoceptors expressed in human embryonic kidney cells. 2013 Naunyn Schmiedebergs Arch. Pharmacol. pmid:23756578
Choi HK et al. PKA negatively regulates PP2Cβ to activate NF-κB-mediated inflammatory signaling. 2013 Biochem. Biophys. Res. Commun. pmid:23756813
Brandherm I et al. cAMP-induced secretion of endothelial von Willebrand factor is regulated by a phosphorylation/dephosphorylation switch in annexin A2. 2013 Blood pmid:23757730
Flores-Clemente C et al. A single-point mutation (Ala280Val) in the third intracellular loop alters the signalling properties of the human histamine H₃ receptor stably expressed in CHO-K1 cells. 2013 Br. J. Pharmacol. pmid:23713487
Derkach KV et al. [Functional activity of adenylyl and guanylyl cyclases in human spermatozoa with different motility]. 2013 Tsitologiia pmid:23718074
Gantz SC et al. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor. 2013 Neuron pmid:23764286
Wang Q and Traynor JR Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells. 2013 Mol. Pharmacol. pmid:23197645
Robins GG et al. Rapid stimulation of human renal ENaC by cAMP in Xenopus laevis oocytes. 2013 J. Physiol. Biochem. pmid:23184731
Amaro-Ortiz A et al. Pharmacologic induction of epidermal melanin and protection against sunburn in a humanized mouse model. 2013 J Vis Exp pmid:24056496
Kabbesh N et al. Vasorelaxant effect of propentofylline in isolated equine digital veins. 2013 Eur. J. Pharmacol. pmid:24051271
Oue T et al. Hedgehog signal inhibitors suppress the invasion of human rhabdomyosarcoma cells. 2013 Pediatr. Surg. Int. pmid:23989521
Koinuma S et al. Regional circadian period difference in the suprachiasmatic nucleus of the mammalian circadian center. 2013 Eur. J. Neurosci. pmid:23869693
Toneatto J et al. Dynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation. 2013 J. Cell. Sci. pmid:24101724
Nakamura Y et al. FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1. 2013 Biochem. Biophys. Res. Commun. pmid:24129192
Wertheimer E et al. Compartmentalization of distinct cAMP signaling pathways in mammalian sperm. 2013 J. Biol. Chem. pmid:24129574
Su H et al. Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradation. 2013 Am. J. Physiol. Renal Physiol. pmid:24133116
Kalim KW and Groettrup M Prostaglandin E2 inhibits IL-23 and IL-12 production by human monocytes through down-regulation of their common p40 subunit. 2013 Mol. Immunol. pmid:22982753
Gomis J et al. Forskolin improves the cryosurvival of in vivo-derived porcine embryos at very early stages using two vitrification methods. 2013 Cryobiology pmid:23313786
Alda M et al. Alterations in phosphorylated cAMP response element-binding protein (pCREB) signaling: an endophenotype of lithium-responsive bipolar disorder? 2013 Bipolar Disord pmid:24238631
Iwasaki R et al. Molecular and pharmacological characterization of zebrafish 'contractile' and 'inhibitory' prostanoid receptors. 2013 Biochem. Biophys. Res. Commun. pmid:23892039
Zeng HT et al. Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence. 2013 Hum. Reprod. pmid:23559189
Vijftigschild LA et al. A novel fluorescent sensor for measurement of CFTR function by flow cytometry. 2013 Cytometry A pmid:23463616
Pignatelli A et al. The h-current in periglomerular dopaminergic neurons of the mouse olfactory bulb. 2013 PLoS ONE pmid:23418585
Follin-Arbelet V et al. Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway. 2013 Cancer Lett. pmid:23454584
Hadad I et al. Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes. 2013 PLoS ONE pmid:23460790
Burdyga A et al. cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC. 2013 Biochim. Biophys. Acta pmid:23797058
McFadden SA et al. Glucose responsiveness in a novel adult-derived GnRH cell line, mHypoA-GnRH/GFP: involvement of AMP-activated protein kinase. 2013 Mol. Cell. Endocrinol. pmid:23835445
Liu ML et al. Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. 2013 Nat Commun pmid:23873306
Wu RY et al. Effect of cAMP on short-circuit current in isolated human ciliary body. 2013 Chin. Med. J. pmid:23876898
Murk K et al. The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. 2013 J. Cell. Sci. pmid:23843614
Wiseman SL et al. Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase. 2013 J. Biol. Chem. pmid:23640883
Liu KC and Ge W Evidence for gating roles of protein kinase A and protein kinase C in estradiol-induced luteinizing hormone receptor (lhcgr) expression in zebrafish ovarian follicle cells. 2013 PLoS ONE pmid:23658740
Yarani R et al. New procedure for epidermal cell isolation using kiwi fruit actinidin, and improved culture of melanocytes in the presence of leukaemia inhibitory factor and forskolin. 2013 Cell Prolif. pmid:23659789
Nebbioso M et al. Treatment of glaucomatous patients by means of food supplement to reduce the ocular discomfort: a double blind randomized trial. 2013 Eur Rev Med Pharmacol Sci pmid:23661528
Canepa E et al. Cyclic adenosine monophosphate as an endogenous modulator of the amyloid-β precursor protein metabolism. 2013 IUBMB Life pmid:23297063
Naderi EH et al. Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL. 2013 Blood pmid:23299313
Cuello C et al. Effect of MEM vitamins and forskolin on embryo development and vitrification tolerance of in vitro-produced pig embryos. 2013 Anim. Reprod. Sci. pmid:23238049
Organ-Darling LE et al. Interactions between hERG and KCNQ1 α-subunits are mediated by their COOH termini and modulated by cAMP. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:23241319
Klepper K and Drabløs F MotifLab: a tools and data integration workbench for motif discovery and regulatory sequence analysis. 2013 BMC Bioinformatics pmid:23323883
Chang ZY et al. Erythropoietin protects adult retinal ganglion cells against NMDA-, trophic factor withdrawal-, and TNF-α-induced damage. 2013 PLoS ONE pmid:23383140
Ganguly A and Lee D Suppression of inhibitory GABAergic transmission by cAMP signaling pathway: alterations in learning and memory mutants. 2013 Eur. J. Neurosci. pmid:23387411
Molosh AI et al. NPY Y1 receptors differentially modulate GABAA and NMDA receptors via divergent signal-transduction pathways to reduce excitability of amygdala neurons. 2013 Neuropsychopharmacology pmid:23358240
Heo H et al. Upregulation of TrkB by forskolin facilitated survival of MSC and functional recovery of memory deficient model rats. 2013 Biochem. Biophys. Res. Commun. pmid:23313493
Danaher RJ et al. C-terminal trans-activation sub-region of VP16 is uniquely required for forskolin-induced herpes simplex virus type 1 reactivation from quiescently infected-PC12 cells but not for replication in neuronally differentiated-PC12 cells. 2013 J. Neurovirol. pmid:23192733