| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Tumor Virus Infections | D014412 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
forskolin
Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of forskolin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with forskolin?
forskolin is suspected in Cyst, Kozlowski Celermajer Tink syndrome, Vocal cord dysfunction familial, Alzheimer's Disease, Cholestasis, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with forskolin
PubChem Associated disorders and diseases
What pathways are associated with forskolin
Lipid pathways are not clear in current pathway databases. We organized associated pathways with forskolin through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with forskolin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with forskolin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with forskolin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with forskolin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with forskolin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with forskolin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Micholt E et al. | Primary culture of embryonic rat olfactory receptor neurons. | 2012 | In Vitro Cell. Dev. Biol. Anim. | pmid:23150136 |
| Meye FJ et al. | Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. | 2012 | J. Neurosci. | pmid:23152596 |
| Matsumiya W et al. | Forskolin modifies retinal vascular development in Mrp4-knockout mice. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:23154460 |
| Shaikh AG and Finlayson PG | Forskolin induced increase in spontaneous activity of auditory brainstem neurons is comparable to acoustic stimulus evoked responses. | 2012 | Neurosci. Lett. | pmid:23127850 |
| Li F et al. | Hormonal induction of polo-like kinases (Plks) and impact of Plk2 on cell cycle progression in the rat ovary. | 2012 | PLoS ONE | pmid:22870256 |
| Oishi H et al. | Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:22610350 |
| Tajima T et al. | EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22159280 |
| Asada Y et al. | Labdane-type diterpenoids from hairy root cultures of Coleus forskohlii, possible intermediates in the biosynthesis of forskolin. | 2012 | Phytochemistry | pmid:22552278 |
| Maruyama I et al. | Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22552730 |
| Kinast L et al. | Impairment of adenylyl cyclase 2 function and expression in hypoxanthine phosphoribosyltransferase-deficient rat B103 neuroblastoma cells as model for Lesch-Nyhan disease: BODIPY-forskolin as pharmacological tool. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22552731 |
| Emery AC and Eiden LE | Signaling through the neuropeptide GPCR PACâ‚ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor. | 2012 | FASEB J. | pmid:22532442 |
| Xu X et al. | Aptameric peptide for one-step detection of protein kinase. | 2012 | Anal. Chem. | pmid:22533554 |
| Mizuta K et al. | The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21964403 |
| Zhao KQ et al. | A role for two-pore K⺠channels in modulating Na⺠absorption and Cl⻠secretion in normal human bronchial epithelial cells. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21964404 |
| Hudson BD and Kelly ME | Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells. | 2012 | J Ocul Pharmacol Ther | pmid:22010988 |
| Murphy SV et al. | Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator. | 2012 | PLoS ONE | pmid:23029546 |
| Törmänen Persson H et al. | Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing. | 2012 | PLoS ONE | pmid:22363758 |
| Edinger RS et al. | The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation. | 2012 | PLoS ONE | pmid:23029554 |
| Astakhova LA et al. | cAMP controls rod photoreceptor sensitivity via multiple targets in the phototransduction cascade. | 2012 | J. Gen. Physiol. | pmid:23008435 |
| Scott TL et al. | Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation. | 2012 | Exp. Dermatol. | pmid:23078399 |
| Cardinali G et al. | Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo. | 2012 | Ann Dermatol Venereol | pmid:23522630 |
| Gimenez-Maitre A et al. | Deficit of osteoprotegerin release by osteoblasts from a patient with cystic fibrosis. | 2012 | Eur. Respir. J. | pmid:22379154 |
| Zeng B et al. | Store-independent pathways for cytosolic STIM1 clustering in the regulation of store-operated Ca(2+) influx. | 2012 | Biochem. Pharmacol. | pmid:22842488 |
| Reitmair A et al. | C6orf176: a novel possible regulator of cAMP-mediated gene expression. | 2012 | Physiol. Genomics | pmid:22108211 |
| Cheung AY et al. | X-chromosome inactivation in rett syndrome human induced pluripotent stem cells. | 2012 | Front Psychiatry | pmid:22470355 |
| Nemere I et al. | Role of the 1,25D3-MARRS receptor in the 1,25(OH)2D3-stimulated uptake of calcium and phosphate in intestinal cells. | 2012 | Steroids | pmid:22546984 |
| Van Hook MJ et al. | Dopaminergic modulation of ganglion-cell photoreceptors in rat. | 2012 | Eur. J. Neurosci. | pmid:22304466 |
| Sampaio Lde F et al. | Linalool from rosewood (Aniba rosaeodora Ducke) oil inhibits adenylate cyclase in the retina, contributing to understanding its biological activity. | 2012 | Phytother Res | pmid:21544884 |
| Li M et al. | Insulin-like growth factor 3 regulates expression of genes encoding steroidogenic enzymes and key transcription factors in the Nile tilapia gonad. | 2012 | Biol. Reprod. | pmid:22337331 |
| Zhou H et al. | Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models. | 2012 | Am. J. Physiol. Renal Physiol. | pmid:22338085 |
| Watanabe K et al. | Latent process genes for cell differentiation are common decoders of neurite extension length. | 2012 | J. Cell. Sci. | pmid:22344266 |
| Vargas A et al. | A new luciferase-based quantitative assay for the evaluation of human trophoblast fusion. | 2012 | Reprod Sci | pmid:22344723 |
| Singh AK et al. | Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid. | 2012 | FASEB J. | pmid:22253479 |
| van Staveren WC et al. | Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes. | 2012 | Exp. Cell Res. | pmid:22240166 |
| Xu G et al. | Depolymerization of cortical actin inhibits UT-A1 urea transporter endocytosis but promotes forskolin-stimulated membrane trafficking. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22262062 |
| Liu Y et al. | Human tau may modify glucocorticoids-mediated regulation of cAMP-dependent kinase and phosphorylated cAMP response element binding protein. | 2012 | Neurochem. Res. | pmid:22294156 |
| Al-Tawashi A et al. | Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity. | 2012 | J. Biol. Chem. | pmid:22375002 |
| Bridges RJ | Mechanisms of bicarbonate secretion: lessons from the airways. | 2012 | Cold Spring Harb Perspect Med | pmid:22908201 |
| Fradet S et al. | Involvement of membrane GRP78 in trophoblastic cell fusion. | 2012 | PLoS ONE | pmid:22912664 |
| Makinodan E and Marneros AG | Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin. | 2012 | Exp. Dermatol. | pmid:23163650 |
| Makino Y et al. | Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle. | 2012 | Allergol Int | pmid:22441633 |
| Nguyen C et al. | Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway. | 2012 | BMC Microbiol. | pmid:22230035 |
| Yao Z et al. | Fractionation of a herbal antidiarrheal medicine reveals eugenol as an inhibitor of Ca2+-Activated Cl- channel TMEM16A. | 2012 | PLoS ONE | pmid:22666439 |
| Delbin MA et al. | Interaction between serotoninergic-and β-adrenergic receptors signaling pathways in rat femoral artery. | 2012 | Arq. Bras. Cardiol. | pmid:22159404 |
| Staruschenko A and Sorokin A | Role of βPix in the Kidney. | 2012 | Front Physiol | pmid:22654768 |
| Kravchenko IV et al. | Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes. | 2012 | Mol. Cell. Biochem. | pmid:22160926 |
| Xing Y et al. | Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL). | 2012 | Endocrinology | pmid:22186415 |
| Roberts KE et al. | Computational design of a PDZ domain peptide inhibitor that rescues CFTR activity. | 2012 | PLoS Comput. Biol. | pmid:22532795 |
| Ohland CL et al. | Escherichia coli-induced epithelial hyporesponsiveness to secretagogues is associated with altered CFTR localization. | 2012 | Cell. Microbiol. | pmid:22212348 |
| Lee H et al. | Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22454682 |
| Rittiner JE et al. | AMP is an adenosine A1 receptor agonist. | 2012 | J. Biol. Chem. | pmid:22215671 |
| Cougot D et al. | Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcription. | 2012 | Sci Signal | pmid:22215732 |
| Huhn R et al. | Age-related loss of cardiac preconditioning: impact of protein kinase A. | 2012 | Exp. Gerontol. | pmid:22100641 |
| Komatsu S et al. | Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes. | 2012 | J. Cell. Physiol. | pmid:22105697 |
| Liu Y et al. | Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats. | 2012 | Endocrinology | pmid:22109884 |
| Córdoba-Chacón J et al. | Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis). | 2012 | Endocrinology | pmid:22109886 |
| Pesce L et al. | TSH regulates pendrin membrane abundance and enhances iodide efflux in thyroid cells. | 2012 | Endocrinology | pmid:22109890 |
| Bzik VA et al. | Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its antidiarrhoeal actions. | 2012 | J. Pharm. Pharmacol. | pmid:22471360 |
| Chung JW et al. | Seminiferous cord formation is regulated by hedgehog signaling in the marsupial. | 2012 | Biol. Reprod. | pmid:22133695 |
| Gao R et al. | Methylseleninic acid is a novel suppressor of aromatase expression. | 2012 | J. Endocrinol. | pmid:22128327 |
| Damdindorj B et al. | Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet β-cells. | 2012 | FEBS Lett. | pmid:22750144 |
| Li R et al. | Neuropeptide Y potentiates beta-adrenergic stimulation of lipolysis in 3T3-L1 adipocytes. | 2012 | Regul. Pept. | pmid:22750277 |
| Spencer S et al. | A mutation in CLOCK leads to altered dopamine receptor function. | 2012 | J. Neurochem. | pmid:22757753 |
| Al-Nakkash L | Genistein stimulates jejunal chloride secretion via sex-dependent, estrogen receptor or adenylate cyclase mechanisms. | 2012 | Cell. Physiol. Biochem. | pmid:22759962 |
| Irwin DA and Van Der Kraak G | Regulation and actions of insulin-like growth factors in the ovary of zebrafish (Danio rerio). | 2012 | Gen. Comp. Endocrinol. | pmid:22484028 |
| Adamson RH et al. | Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22427519 |
| Plouffe B et al. | The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner. | 2012 | Cell. Signal. | pmid:21893192 |
| Ehrlund A et al. | Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells. | 2012 | PLoS ONE | pmid:22427816 |
| Kambe Y and Miyata A | Role of mitochondrial activation in PACAP dependent neurite outgrowth. | 2012 | J. Mol. Neurosci. | pmid:22460784 |
| Forgacs AL et al. | BLTK1 murine Leydig cells: a novel steroidogenic model for evaluating the effects of reproductive and developmental toxicants. | 2012 | Toxicol. Sci. | pmid:22461451 |
| Chen B et al. | Pharmacologic agents elevating cAMP prevent arginase II expression and proliferation of pulmonary artery smooth muscle cells. | 2012 | Am. J. Respir. Cell Mol. Biol. | pmid:22447968 |
| Dean C et al. | Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. | 2012 | J. Neurosci. | pmid:22514304 |
| Zheng F et al. | M2 muscarinic acetylcholine receptors regulate long-term potentiation at hippocampal CA3 pyramidal cell synapses in an input-specific fashion. | 2012 | J. Neurophysiol. | pmid:22490561 |
| Ji H et al. | Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice. | 2012 | Liver Transpl. | pmid:22290937 |
| Hing B et al. | A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity. | 2012 | Biol. Psychiatry | pmid:22265241 |
| Franko-Tobin LG et al. | Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics. | 2012 | Oncologist | pmid:22291092 |
| Kwiecinska P et al. | Hydroxylated estrogens (2-OH-E2 AND 4-OH-E2) do not activate cAMP/PKA and ERK1/2 pathways activation in a breast cancer MCF-7 cell line. | 2012 | Endocr Regul | pmid:22329816 |
| Aoki T et al. | Close association of aquaporin-2 internalization with caveolin-1. | 2012 | Acta Histochem Cytochem | pmid:22685356 |
| Börner C et al. | Mechanisms of the inhibition of nuclear factor-κB by morphine in neuronal cells. | 2012 | Mol. Pharmacol. | pmid:22258905 |
| Banerjee A and Onyuksel H | Human pancreatic polypeptide in a phospholipid-based micellar formulation. | 2012 | Pharm. Res. | pmid:22399387 |
| Gbahou F et al. | The histamine autoreceptor is a short isoform of the H₃ receptor. | 2012 | Br. J. Pharmacol. | pmid:22356432 |
| Salma J and McDermott JC | Suppression of a MEF2-KLF6 survival pathway by PKA signaling promotes apoptosis in embryonic hippocampal neurons. | 2012 | J. Neurosci. | pmid:22357862 |
| Khurana S et al. | An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision. | 2012 | J. Neurosci. | pmid:22357864 |
| Darios ES et al. | Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22366660 |
| Hwang TL et al. | YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22381622 |
| Punn A et al. | Mapping structural determinants within third intracellular loop that direct signaling specificity of type 1 corticotropin-releasing hormone receptor. | 2012 | J. Biol. Chem. | pmid:22247544 |
| Procino G et al. | Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study. | 2012 | PLoS ONE | pmid:22403735 |
| Liu ZJ et al. | Intestinal permeability of forskolin by in situ single pass perfusion in rats. | 2012 | Planta Med. | pmid:22411728 |
| Choi S et al. | Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism. | 2012 | Pharmacol. Res. | pmid:22414869 |
| Zhao LF et al. | Liver X receptor α is involved in the transcriptional regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene. | 2012 | Diabetes | pmid:22415873 |
| Katsuyama M et al. | Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme. | 2012 | J Clin Biochem Nutr | pmid:22247596 |
| Bellanger S et al. | Saturated fatty acid exposure induces androgen overproduction in bovine adrenal cells. | 2012 | Steroids | pmid:22245830 |
| Li Y et al. | Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis. | 2012 | PLoS ONE | pmid:22384126 |
| Tanaka H et al. | Application of Monoclonal Antibodies against Bioactive Natural Products: Eastern Blotting and Preparation of Knockout Extract. | 2012 | Int J Anal Chem | pmid:22518137 |
| Nebbioso M et al. | Forskolin and rutin prevent intraocular pressure spikes after Nd:YAG laser iridotomy. | 2012 | Panminerva Med | pmid:23241939 |
| Tu J et al. | cAMP/protein kinase A activates cystic fibrosis transmembrane conductance regulator for ATP release from rat skeletal muscle during low pH or contractions. | 2012 | PLoS ONE | pmid:23226244 |
| Jiwaji M et al. | Unique reporter-based sensor platforms to monitor signalling in cells. | 2012 | PLoS ONE | pmid:23209767 |
| Witkowski G et al. | Effect of cyclic adenosine monophosphate on the G protein-dependent inward rectifier K(+)-like channel current in medial prefrontal cortex pyramidal neurons. | 2012 | J. Physiol. Pharmacol. | pmid:23211299 |
| Cheng Y et al. | Intraovarian thrombin and activated protein C signaling system regulates steroidogenesis during the periovulatory period. | 2012 | Mol. Endocrinol. | pmid:22207716 |
| Yokotani K et al. | Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro. | 2012 | J. Pharm. Pharmacol. | pmid:23146043 |