Abietic acid is a lipid of Prenol Lipids (PR) class. Abietic acid is associated with abnormalities such as Hand eczema, Dermatitis, Vitelliform dystrophy, Wiskott-Aldrich Syndrome and Dehydration. The involved functions are known as Process, Oxidation, Anabolism, Transmembrane Transport and physiological aspects. Abietic acid often locates in Membrane, Protoplasm, Microsomes and Cellular Membrane. The associated genes with Abietic acid are SLC33A1 gene and ABCG2 gene. The related lipids are Pinene.
To understand associated biological information of Abietic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Abietic acid is suspected in Hand eczema, Dermatitis, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Abietic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Ulcer | D014456 | 16 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lauriola MM et al. | Allergic contact dermatitis from depilatory wax. | 2012 May-Jun | Dermatitis | pmid:22653175 |
| Yoshida N et al. | Inhibitory effects of terpenoids on multidrug resistance-associated protein 2- and breast cancer resistance protein-mediated transport. | 2008 | Drug Metab. Dispos. | pmid:18436619 |
| Oppel T and Schnuch A | [The most frequent allergens in allergic contact dermatitis]. | 2006 | Dtsch. Med. Wochenschr. | pmid:16823706 |
| Pacheco M and Santos MA | Induction of EROD activity and genotoxic effects by polycyclic aromatic hydrocarbons and resin acids on the juvenile eel (Anguilla anguilla L.). | 1997 | Ecotoxicol. Environ. Saf. | pmid:9469877 |
| Gravato C and Santos MA | Juvenile sea bass liver biotransformation induction and erythrocytic genotoxic responses to resin acids. | 2002 | Ecotoxicol. Environ. Saf. | pmid:12297086 |
| Maria VL et al. | Anguilla anguilla L. genotoxic and liver biotransformation responses to abietic acid exposure. | 2004 | Ecotoxicol. Environ. Saf. | pmid:15157574 |
| Kamaya Y et al. | Effects of dehydroabietic acid and abietic acid on survival, reproduction, and growth of the crustacean Daphnia magna. | 2005 | Ecotoxicol. Environ. Saf. | pmid:15814313 |
| Gravato C et al. | Oxidative stress and genotoxic responses to resin acids in Mediterranean mussels. | 2005 | Ecotoxicol. Environ. Saf. | pmid:15883093 |
| Teles M et al. | Anguilla anguilla L. plasma cortisol, lactate and glucose responses to abietic acid, dehydroabietic acid and retene. | 2004 | Environ Int | pmid:14592577 |
| Quinn BP et al. | Selected resin acids in effluent and receiving waters derived from a bleached and unbleached kraft pulp and paper mill. | 2003 | Environ. Toxicol. Chem. | pmid:12503767 |
| González MA et al. | Synthesis and biological evaluation of abietic acid derivatives. | 2009 | Eur J Med Chem | pmid:19217699 |
| González MA et al. | Synthesis and biological evaluation of dehydroabietic acid derivatives. | 2010 | Eur J Med Chem | pmid:19892441 |
| Sadashiva MP et al. | A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activity. | 2015 | Exp. Parasitol. | pmid:25982031 |
| Takahashi N et al. | Abietic acid activates peroxisome proliferator-activated receptor-gamma (PPARgamma) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism. | 2003 | FEBS Lett. | pmid:12935909 |
| Orpiszewski J et al. | Multiple forms of O-methyltransferase involved in the microbial conversion of abietic acid into methyl abietate by Mycobacterium sp. | 1991 | FEMS Microbiol. Lett. | pmid:1936951 |
| Ozaki A et al. | Safety assessment of paper and board food packaging: chemical analysis and genotoxicity of possible contaminants in packaging. | 2005 | Food Addit Contam | pmid:16227189 |
| Ozaki A et al. | Migration of dehydroabietic and abietic acids from paper and paperboard food packaging into food-simulating solvents and Tenax TA. | 2006 | Food Addit Contam | pmid:16807212 |
| Ohmori K and Kawamura Y | Cell transformation activities of abietic acid and dehydroabietic acid: safety assessment of possible contaminants in paper and paperboard for food contact use. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680931 |
| Bhatia SP et al. | Fragrance material review on abietyl acetate. | 2008 | Food Chem. Toxicol. | pmid:18845214 |
| Lardos A et al. | Resins and Gums in Historical Iatrosophia Texts from Cyprus - A Botanical and Medico-pharmacological Approach. | 2011 | Front Pharmacol | pmid:21772820 |