Abietic acid is a lipid of Prenol Lipids (PR) class. Abietic acid is associated with abnormalities such as Hand eczema, Dermatitis, Vitelliform dystrophy, Wiskott-Aldrich Syndrome and Dehydration. The involved functions are known as Process, Oxidation, Anabolism, Transmembrane Transport and physiological aspects. Abietic acid often locates in Membrane, Protoplasm, Microsomes and Cellular Membrane. The associated genes with Abietic acid are SLC33A1 gene and ABCG2 gene. The related lipids are Pinene.
To understand associated biological information of Abietic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Abietic acid is suspected in Hand eczema, Dermatitis, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Abietic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
| Ulcer | D014456 | 16 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Asthma | D001249 | 52 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:17352501 | ||||
| Patel GB et al. | Inhibition of pure cultures of methanogens by benzene ring compounds. | 1991 | Appl. Environ. Microbiol. | pmid:1746956 |
| pmid:17577378 | ||||
| Smith DJ et al. | A large gene cluster in Burkholderia xenovorans encoding abietane diterpenoid catabolism. | 2007 | J. Bacteriol. | pmid:17586638 |
| Puranik PK and Dorle AK | Study of abietic acid glycerol derivatives as microencapsulating materials. | 1991 Apr-Jun | J Microencapsul | pmid:1765905 |
| Smith DJ et al. | Distinct roles for two CYP226 family cytochromes P450 in abietane diterpenoid catabolism by Burkholderia xenovorans LB400. | 2008 | J. Bacteriol. | pmid:18156276 |
| Eriksson K et al. | Tape-stripping as a method for measuring dermal exposure to resin acids during wood pellet production. | 2008 | J Environ Monit | pmid:18392277 |
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| pmid:18666177 | ||||
| Di Paolo RE et al. | Picosecond structural relaxation of abietic acid based amine end capped para-phenylenevinylene trimers in solution. | 2008 | Chemphyschem | pmid:18830995 |
| Bhatia SP et al. | Fragrance material review on abietyl acetate. | 2008 | Food Chem. Toxicol. | pmid:18845214 |
| Samoylenko V et al. | Antiparasitic, nematicidal and antifouling constituents from Juniperus berries. | 2008 | Phytother Res | pmid:19067375 |
| Wiyono B et al. | Reaction of abietic acid with maleic anhydride and fumaric acid and attempts to find the fundamental component of fortified rosin. | 2007 | Pak. J. Biol. Sci. | pmid:19086503 |
| pmid:19101885 | ||||
| González MA et al. | Synthesis and biological evaluation of abietic acid derivatives. | 2009 | Eur J Med Chem | pmid:19217699 |
| Orpiszewski J et al. | Multiple forms of O-methyltransferase involved in the microbial conversion of abietic acid into methyl abietate by Mycobacterium sp. | 1991 | FEMS Microbiol. Lett. | pmid:1936951 |
| Assalin MR et al. | Combined system of activated sludge and ozonation for the treatment of kraft E1 effluent. | 2009 | Int J Environ Res Public Health | pmid:19440438 |
| Ohmori K and Kawamura Y | Cell transformation activities of abietic acid and dehydroabietic acid: safety assessment of possible contaminants in paper and paperboard for food contact use. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680931 |
| González MA et al. | Synthesis and biological evaluation of dehydroabietic acid derivatives. | 2010 | Eur J Med Chem | pmid:19892441 |
| Yang XW et al. | Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. | 2010 | Bioorg. Med. Chem. | pmid:20022253 |
| Keeling CI et al. | Identification and functional characterization of monofunctional ent-copalyl diphosphate and ent-kaurene synthases in white spruce reveal different patterns for diterpene synthase evolution for primary and secondary metabolism in gymnosperms. | 2010 | Plant Physiol. | pmid:20044448 |
| Jung MJ et al. | A new abietic acid-type diterpene glucoside from the needles of Pinus densiflora. | 2009 | Arch. Pharm. Res. | pmid:20162397 |
| Kim NH et al. | Tetrahydroabietic Acid, a Reduced Abietic Acid, Inhibits the Production of Inflammatory Mediators in RAW264.7 Macrophages Activated with Lipopolysaccharide. | 2010 | J Clin Biochem Nutr | pmid:20216944 |
| Hirai S et al. | Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies. | 2010 | Mediators Inflamm. | pmid:20508825 |
| Söderberg TA et al. | Antibacterial effects of zinc oxide, rosin, and resin acids with special reference to their interactions. | 1991 | Scand J Plast Reconstr Surg Hand Surg | pmid:2052904 |
| Abbott E et al. | Laser microdissection of conifer stem tissues: isolation and analysis of high quality RNA, terpene synthase enzyme activity and terpenoid metabolites from resin ducts and cambial zone tissue of white spruce (Picea glauca). | 2010 | BMC Plant Biol. | pmid:20540781 |
| pmid:20583317 | ||||
| Goto T et al. | Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. | 2010 | PPAR Res | pmid:20613991 |
| Hausen BM et al. | Contact allergy due to colophony (VII). Sensitizing studies with oxidation products of abietic and related acids. | 1990 | Contact Derm. | pmid:2096024 |
| Ehrin E and Karlberg AT | Detection of rosin (colophony) components in technical products using an HPLC technique. | 1990 | Contact Derm. | pmid:2096025 |
| Boskabady MH et al. | Work-related respiratory symptoms and pulmonary function tests in northeast iranian (the city of Mashhad) carpenters. | 2010 | Clinics (Sao Paulo) | pmid:21120301 |
| pmid:21146981 | ||||
| Gören AC et al. | Chemical composition of natural colophony from Pinus brutia and comparison with synthetic colophony. | 2010 | Nat Prod Commun | pmid:21213968 |
| Bleif S et al. | Identification of CYP106A2 as a regioselective allylic bacterial diterpene hydroxylase. | 2011 | Chembiochem | pmid:21271628 |
| Siebert MR et al. | The need for enzymatic steering in abietic acid biosynthesis: gas-phase chemical dynamics simulations of carbocation rearrangements on a bifurcating potential energy surface. | 2011 | J. Am. Chem. Soc. | pmid:21548620 |
| Zhang M et al. | Maleopimaric acid acetic acid solvate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21582965 |
| Zhang M et al. | 13-Ethoxy-carbonyl-16-(1-methyl-ethyl)-17,19-dinoratis-15-ene-4,14-dicarboxylic acid monohydrate: a new derivative of maleopimaric acid. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583637 |
| Wang K et al. | Methyl 7-oxo-12-propyl-amino-13-nitro-deisopropyl-dehydro-abietate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21587581 |
| Rao XP | N-Morpholino-Δ-dihydro-abietamide. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588936 |
| Frija LM et al. | Isolation, chemical, and biotransformation routes of labdane-type diterpenes. | 2011 | Chem. Rev. | pmid:21618966 |
| Lardos A et al. | Resins and Gums in Historical Iatrosophia Texts from Cyprus - A Botanical and Medico-pharmacological Approach. | 2011 | Front Pharmacol | pmid:21772820 |
| Hwang KH et al. | Abietic acid has an anti-obesity effect in mice fed a high-fat diet. | 2011 | J Med Food | pmid:21812648 |
| Axelsson S et al. | Determination of resin acids during production of wood pellets--a comparison of HPLC/ESI-MS with the GC/FID MDHS 83/2 method. | 2011 | J Environ Monit | pmid:21874165 |
| Schmidt A et al. | Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). | 2011 | Plant Mol. Biol. | pmid:22002747 |
| pmid:22008013 | ||||
| pmid:22020363 | ||||
| pmid:22274948 | ||||
| Suhng EA et al. | A Case of Allergic Contact Dermatitis Due to DuoDERM Extrathin®. | 2011 | Ann Dermatol | pmid:22346285 |
| pmid:22426093 | ||||
| He Y et al. | Isolation and structural elucidation of abietic acid as the main adulterant in an herbal drug for the treatment of psoriasis. | 2012 | J Pharm Biomed Anal | pmid:22482903 |