Abietic acid is a lipid of Prenol Lipids (PR) class. Abietic acid is associated with abnormalities such as Hand eczema, Dermatitis, Vitelliform dystrophy, Wiskott-Aldrich Syndrome and Dehydration. The involved functions are known as Process, Oxidation, Anabolism, Transmembrane Transport and physiological aspects. Abietic acid often locates in Membrane, Protoplasm, Microsomes and Cellular Membrane. The associated genes with Abietic acid are SLC33A1 gene and ABCG2 gene. The related lipids are Pinene.
To understand associated biological information of Abietic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Abietic acid is suspected in Hand eczema, Dermatitis, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Abietic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
| Ulcer | D014456 | 16 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Asthma | D001249 | 52 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matsuya Y and Matsuya S | Effect of abietic acid and poly(methyl methacrylate) on the dissolution process of zinc oxide-eugenol cement. | 1994 | Biomaterials | pmid:8031992 |
| Kazakova OB et al. | [Synthesis, structure and farmacologycal activity of (7R,8S)-epoxy-(13R,17R)-trioxolaneabietic acid]. | 2013 Mar-Apr | Bioorg. Khim. | pmid:23964524 |
| Gigante B et al. | Catechols from abietic acid synthesis and evaluation as bioactive compounds. | 2003 | Bioorg. Med. Chem. | pmid:12659748 |
| Yang XW et al. | Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. | 2010 | Bioorg. Med. Chem. | pmid:20022253 |
| Talevi A et al. | Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17234417 |
| Yao F et al. | Preparation and application of abietic acid-derived optically active helical polymers and their chiral hydrogels. | 2013 | Bioresour. Technol. | pmid:23232223 |
| Mitsukura K et al. | Regio- and stereo-selective hydroxylation of abietic acid derivatives by Mucor circinelloides and Mortierella isabellina. | 2005 | Biotechnol. Lett. | pmid:16215830 |
| Clement YN et al. | Medicinal herb use among asthmatic patients attending a specialty care facility in Trinidad. | 2005 | BMC Complement Altern Med | pmid:15713232 |
| Gambichler T et al. | Contact dermatitis and other skin conditions in instrumental musicians. | 2004 | BMC Dermatol. | pmid:15090069 |
| Abbott E et al. | Laser microdissection of conifer stem tissues: isolation and analysis of high quality RNA, terpene synthase enzyme activity and terpenoid metabolites from resin ducts and cambial zone tissue of white spruce (Picea glauca). | 2010 | BMC Plant Biol. | pmid:20540781 |
| Karlberg AT and Lidén C | Colophony (rosin) in newspapers may contribute to hand eczema. | 1992 | Br. J. Dermatol. | pmid:1536781 |
| Sadhra S et al. | Identification of contact allergens in unmodified rosin using a combination of patch testing and analytical chemistry techniques. | 1996 | Br. J. Dermatol. | pmid:8733367 |
| Sousa Neto MD et al. | The influence of different grades of rosins and hydrogenated resins on the powder-liquid ratio of Grossman cements. | 1998 | Braz Dent J | pmid:9835799 |
| Fâhraeus-Van Ree GE and Payne JF | Enzyme cytochemical responses of mussels (Mytilus edulis) to resin acid constituents of pulp mill effluents. | 1999 | Bull Environ Contam Toxicol | pmid:10501718 |
| Belmonte M et al. | Effect of aerobic sludge with increasing level of adaptation on abietic acid biodegradation. | 2006 | Bull Environ Contam Toxicol | pmid:17219306 |
| Morgan CA and Wyndham RC | Characterization of tdt genes for the degradation of tricyclic diterpenes by Pseudomonas diterpeniphila A19-6a. | 2002 | Can. J. Microbiol. | pmid:11888163 |
| Shpatov AV et al. | Lipophilic extracts from needles and defoliated twigs of Pinus pumila from two different populations. | 2013 | Chem. Biodivers. | pmid:23418167 |
| Fujita Y et al. | New hypocholesterolemic abietamide derivatives. I. Structure-activity relationship. | 1980 | Chem. Pharm. Bull. | pmid:7389019 |
| Frija LM et al. | Isolation, chemical, and biotransformation routes of labdane-type diterpenes. | 2011 | Chem. Rev. | pmid:21618966 |
| Janocha S et al. | Resin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids. | 2013 | Chembiochem | pmid:23371760 |