MeSH term | MeSH ID | Detail |
---|---|---|
Enterobacteriaceae Infections | D004756 | 5 associated lipids |
Neoplasms, Glandular and Epithelial | D009375 | 12 associated lipids |
Paclitaxel is a lipid of Prenol Lipids (PR) class. Paclitaxel is associated with abnormalities such as Multiple Sulfatase Deficiency Disease, Peripheral Neuropathy, Pulmonary Embolism, Painful Bladder Syndrome and athymia. The involved functions are known as synergism, Metabolic Inhibition, Drug Efflux, Disease regression and Oxidation. Paclitaxel often locates in Back, Hepatic, Microtubules, Head and Cytoskeleton. The associated genes with Paclitaxel are CDAN1 gene, IMPACT gene, ABCB1 gene, BCL2 gene and P4HTM gene. The related lipids are Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of Paclitaxel, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Paclitaxel is suspected in athymia, Multiple Sulfatase Deficiency Disease, Peripheral Neuropathy, Pulmonary Embolism, Painful Bladder Syndrome, Neuropathy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Paclitaxel
MeSH term | MeSH ID | Detail |
---|---|---|
Enterobacteriaceae Infections | D004756 | 5 associated lipids |
Neoplasms, Glandular and Epithelial | D009375 | 12 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Paclitaxel through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.' (Wang E et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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