Paclitaxel

Paclitaxel is a lipid of Prenol Lipids (PR) class. Paclitaxel is associated with abnormalities such as Multiple Sulfatase Deficiency Disease, Peripheral Neuropathy, Pulmonary Embolism, Painful Bladder Syndrome and athymia. The involved functions are known as synergism, Metabolic Inhibition, Drug Efflux, Disease regression and Oxidation. Paclitaxel often locates in Back, Hepatic, Microtubules, Head and Cytoskeleton. The associated genes with Paclitaxel are CDAN1 gene, IMPACT gene, ABCB1 gene, BCL2 gene and P4HTM gene. The related lipids are Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Paclitaxel, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Paclitaxel?

Paclitaxel is suspected in athymia, Multiple Sulfatase Deficiency Disease, Peripheral Neuropathy, Pulmonary Embolism, Painful Bladder Syndrome, Neuropathy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Paclitaxel

MeSH term MeSH ID Detail
Enterobacteriaceae Infections D004756 5 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Paclitaxel

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Paclitaxel through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Paclitaxel?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Paclitaxel?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Paclitaxel?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Paclitaxel?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Paclitaxel?

Xenograft Model

Xenograft Model are used in the study 'The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.' (Wang E et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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