| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
Total
1
Lupeol
Lupeol is a lipid of Prenol Lipids (PR) class. Lupeol is associated with abnormalities such as Morphologically altered structure, Infection, protrusion, Consumption-archaic term for TB and PARAGANGLIOMAS 2. The involved functions are known as Transcriptional Activation, Agent, Tumorigenicity, Signal and inhibitors. Lupeol often locates in Body tissue, Membrane, Cytoplasmic, Stress Fibers and Filopodia. The associated genes with Lupeol are Candidate Disease Gene, SPEN gene, AR gene, SGK1 gene and TIPARP gene. The related lipids are Sterols, Micelles, campesterol, amyrin and campestanol. The related experimental models are Mouse Model and Xenograft Model.
Cross Reference
Introduction
To understand associated biological information of Lupeol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lupeol?
Lupeol is suspected in Parasitemia, Plasmodium falciparum infection, Morphologically altered structure, PARAGANGLIOMAS 2, PARAGANGLIOMAS 3, Acne and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lupeol
PubChem Associated disorders and diseases
What pathways are associated with Lupeol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Lupeol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lupeol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lupeol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lupeol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lupeol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lupeol?
Mouse Model
Mouse Model are used in the study 'Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.' (Lee TK et al., 2007), Mouse Model are used in the study 'Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis.' (Saleem M et al., 2008), Mouse Model are used in the study 'Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.' (Tarapore RS et al., 2010) and Mouse Model are used in the study 'Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling.' (Saleem M et al., 2009).
Xenograft Model
Xenograft Model are used in the study 'Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling.' (Saleem M et al., 2009) and Xenograft Model are used in the study 'Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis.' (Saleem M et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Lupeol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tahsin T et al. | Cytotoxic Properties of the Stem Bark of Citrus reticulata Blanco (Rutaceae). | 2017 | Phytother Res | pmid:28568378 |
| Ghazanfar K et al. | Gentiana kurroo Royle attenuates the metabolic aberrations in diabetic rats; Swertiamarin, swertisin and lupeol being the possible bioactive principles. | 2017 | J Complement Integr Med | pmid:28731312 |
| Singh P et al. | Enhanced chemoprevention by the combined treatment of pterostilbene and lupeol in B[a]P-induced mouse skin tumorigenesis. | 2017 | Food Chem. Toxicol. | pmid:27836749 |
| Ramu R et al. | Assessment of In Vivo Antidiabetic Properties of Umbelliferone and Lupeol Constituents of Banana (Musa sp. var. Nanjangud Rasa Bale) Flower in Hyperglycaemic Rodent Model. | 2016 | PLoS ONE | pmid:27003006 |
| Jin T et al. | Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B. | 2016 | Sci Rep | pmid:26865097 |
| Gajos-Michniewicz A and Czyz M | Modulation of WNT/β-catenin pathway in melanoma by biologically active components derived from plants. | 2016 | Fitoterapia | pmid:26851176 |
| Ambasta RK et al. | Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules. | 2015 | J Transl Med | pmid:26385094 |
| Khakimov B et al. | Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana. | 2015 | Plant J. | pmid:26333142 |
| Kuete V et al. | Cytotoxic compounds from the fruits of Uapaca togoensis towards multifactorial drug-resistant cancer cells. | 2015 | Planta Med. | pmid:25473921 |
| Nguyen HQ et al. | Creation and study of triterpenoid nanoparticles and radioprotective substance genistein. | 2015 | Dokl. Biochem. Biophys. | pmid:26518563 |