MeSH term | MeSH ID | Detail |
---|---|---|
Ear Diseases | D004427 | 7 associated lipids |
Edema | D004487 | 152 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Ear Diseases | D004427 | 7 associated lipids |
Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen S et al. | The protective effect of glycyrrhetinic acid on carbon tetrachloride-induced chronic liver fibrosis in mice via upregulation of Nrf2. | 2013 | PLoS ONE | pmid:23341968 |
Chen H et al. | Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. | 2013 | Mol Nutr Food Res | pmid:23322474 |
Zong L et al. | 18α-glycyrrhetinic acid extracted from Glycyrrhiza radix inhibits proliferation and promotes apoptosis of the hepatic stellate cell line. | 2013 | J Dig Dis | pmid:23362936 |
Lin J et al. | Development of Salvianolic acid B-Tanshinone II A-Glycyrrhetinic acid compound liposomes: formulation optimization and its effects on proliferation of hepatic stellate cells. | 2014 | Int J Pharm | pmid:24374609 |
Kuzma-Kuzniarska M et al. | Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching. | 2014 | J Biomed Opt | pmid:24390370 |
Cheng M et al. | Optimized synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and their characteristics. | 2014 | Int J Nanomedicine | pmid:24493926 |
Du QH et al. | Glytan decreases portal pressure via mesentery vasoconstriction in portal hypertensive rats. | 2014 | World J. Gastroenterol. | pmid:25469036 |
Tang WJ et al. | Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65. | 2014 | Sci Rep | pmid:25407586 |
Tian J et al. | A wogonin-loaded glycyrrhetinic acid-modified liposome for hepatic targeting with anti-tumor effects. | 2014 | Drug Deliv | pmid:24215357 |
Sakata O et al. | Effects of oils and emulsifiers on the skin penetration of stearyl glycyrrhetinate in oil-in-water emulsions. | 2014 | Biol. Pharm. Bull. | pmid:24583868 |