Glycyrrhetinic acid

Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.

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Introduction

To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycyrrhetinic acid?

Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid

PubChem Associated disorders and diseases

What pathways are associated with Glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycyrrhetinic acid?

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What functions are associated with Glycyrrhetinic acid?


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What lipids are associated with Glycyrrhetinic acid?

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What genes are associated with Glycyrrhetinic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Du H et al. The role of glycyrrhetinic acid modification on preparation and evaluation of quercetin-loaded chitosan-based self-aggregates. 2015 J Colloid Interface Sci pmid:26319324
Yang H et al. The protection of glycyrrhetinic acid (GA) towards acetaminophen (APAP)-induced toxicity partially through fatty acids metabolic pathway. 2015 Afr Health Sci pmid:26957996
Lv QL et al. In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4. 2015 Int J Environ Res Public Health pmid:26712778
Tang ZH et al. Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. 2015 Oncotarget pmid:26549806
Hagiwara K et al. A robust screening method for dietary agents that activate tumour-suppressor microRNAs. 2015 Sci Rep pmid:26423775
Li J et al. Synthesis, characterization, and in vitro evaluation of curcumin-loaded albumin nanoparticles surface-functionalized with glycyrrhetinic acid. 2015 Int J Nanomedicine pmid:26346750
Mezghrani O et al. Hepatocellular carcinoma dually-targeted nanoparticles for reduction triggered intracellular delivery of doxorubicin. 2015 Int J Pharm pmid:25455765
Zhou B et al. The influence of compatibility of processed radix Aconiti Kusnezoffii on the pharmacokinetic of four components in Glycyrrhiza uralensis Fisch. 2015 J Ethnopharmacol pmid:25889555
Bhatia C et al. Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. 2015 Chem. Biol. Interact. pmid:25526675
Rino Y et al. Does herbal medicine reduce the risk of hepatocellular carcinoma? 2015 World J. Gastroenterol. pmid:26457019