MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jayasooriya RG et al. | 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. | 2014 | Toxicol In Vitro | pmid:24613819 |
Li X et al. | Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24380838 |
Tang ZH et al. | Glycyrrhetinic Acid triggers a protective autophagy by activation of extracellular regulated protein kinases in hepatocellular carcinoma cells. | 2014 | J. Agric. Food Chem. | pmid:25403108 |
Yuan R et al. | Self-assembled nanoparticles of glycyrrhetic acid-modified pullulan as a novel carrier of curcumin. | 2014 | Molecules | pmid:25170951 |
Muller B et al. | Glycyrrhetinic acid reverses the lipopolysaccharide-induced hypocontractility to noradrenaline in rat aorta: implications to septic shock. | 2014 | J. Pharmacol. Sci. | pmid:25141925 |
Fujita K et al. | Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact. | 2014 | J. Cell. Biochem. | pmid:25043105 |
Wang Q et al. | Content determination of the major constituents of Yinchenzhufu decoction via ultra high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. | 2013 | J Pharm Biomed Anal | pmid:23411001 |
Wu Z et al. | Two new phenolic glycosides from Inula cappa DC. | 2013 | Nat. Prod. Res. | pmid:22676342 |
Termei R et al. | Intercellular interactions between mast cells and fibroblasts promote pro-inflammatory signaling. | 2013 | Exp. Cell Res. | pmid:23578767 |
Kalani K et al. | Glycyrrhetinic acid and its analogs: a new class of antifilarial agents. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23541646 |