| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Ear Diseases | D004427 | 7 associated lipids |
Total
2
Glycyrrhetinic acid
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
Cross Reference
Introduction
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glycyrrhetinic acid?
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
PubChem Associated disorders and diseases
What pathways are associated with Glycyrrhetinic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glycyrrhetinic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Glycyrrhetinic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ploeger BA et al. | Physiologically based pharmacokinetic modeling of glycyrrhizic acid, a compound subject to presystemic metabolism and enterohepatic cycling. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10652246 |
| Shaikh ZA et al. | Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. | 1999 | Toxicol. Appl. Pharmacol. | pmid:9931285 |
| Ploeger B et al. | A population physiologically based pharmacokinetic/pharmacodynamic model for the inhibition of 11-beta-hydroxysteroid dehydrogenase activity by glycyrrhetic acid. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11141355 |
| Jayasooriya RG et al. | 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. | 2014 | Toxicol In Vitro | pmid:24613819 |
| Komoda Y | [Nuclear magnetic resonance spectra of 18-beta-glycyrrhetinic acid and its related compounds]. | 1984 | Tokyo Ika Shika Daigaku Iyo Kizai Kenkyusho Hokoku | pmid:6598495 |
| Takeda H et al. | Eosinophilic peritonitis responding to treatment with glycyrrhizin. | 1991 | Tokai J. Exp. Clin. Med. | pmid:1811351 |
| Numazaki K et al. | Effect of glycyrrhizin in children with liver dysfunction associated with cytomegalovirus infection. | 1994 | Tohoku J. Exp. Med. | pmid:8073426 |
| Mori K et al. | Effects of glycyrrhizin (SNMC: Stronger Neo-Minophagen C) in hemophilia patients with HIV-1 infection. | 1990 | Tohoku J. Exp. Med. | pmid:2129071 |
| Shamsa F et al. | The in vitro effects of glycyrrhizin and the derivatives of glycyrrhetinic acid on the activity of cAMP-dependent protein kinase and phosphorylation of cellular polypeptide by the kinase from Ehrlich ascites tumor cells. | 1991 | Tohoku J. Exp. Med. | pmid:1818438 |
| Mori K et al. | Effects of glycyrrhizin (SNMC: stronger Neo-Minophagen C) in hemophilia patients with HIV infection. | 1989 | Tohoku J. Exp. Med. | pmid:2781539 |