MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Seckl JR et al. | The 11 beta-hydroxysteroid dehydrogenase inhibitor glycyrrhetinic acid affects corticosteroid feedback regulation of hypothalamic corticotrophin-releasing peptides in rats. | 1993 | J. Endocrinol. | pmid:8473834 |
Tabata M et al. | Production of an anti-allergic triterpene bryonolic acid, by plant cell cultures. | 1993 | J. Nat. Prod. | pmid:8463793 |
Addison RS et al. | Pathway and kinetics of prednisolone metabolism in the human placenta. | 1993 | J. Steroid Biochem. Mol. Biol. | pmid:8461264 |
Kawakami J et al. | Kinetic analysis of glycyrrhetic acid, an active metabolite of glycyrrhizin, in rats: role of enterohepatic circulation. | 1993 | J Pharm Sci | pmid:8450426 |
Zhang YH et al. | Glycyrrhizin as a promoter of the late signal transduction for interleukin-2 production by splenic lymphocytes. | 1993 | Immunology | pmid:8406577 |
Kitagawa I et al. | Saponin and sapogenol. XLIX. On the constituents of the roots of Glycyrrhiza inflata Batalin from Xinjiang, China. Characterization of two sweet oleanane-type triterpene oligoglycosides, apioglycyrrhizin and araboglycyrrhizin. | 1993 | Chem. Pharm. Bull. | pmid:8403083 |
Størmer FC et al. | Glycyrrhizic acid in liquorice--evaluation of health hazard. | 1993 | Food Chem. Toxicol. | pmid:8386690 |
Ishii M et al. | A case of drug-induced ductopenia resulting in fatal biliary cirrhosis. | 1993 | Liver | pmid:8377599 |
Nakamura T et al. | Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8363265 |
Kobayashi M et al. | Inhibition of burn-associated suppressor cell generation by glycyrrhizin through the induction of contrasuppressor T cells. | 1993 | Immunol. Cell Biol. | pmid:8349301 |