Glycyrrhetinic acid

Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.

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Introduction

To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycyrrhetinic acid?

Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid

PubChem Associated disorders and diseases

What pathways are associated with Glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Glycyrrhetinic acid?

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What functions are associated with Glycyrrhetinic acid?


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What lipids are associated with Glycyrrhetinic acid?

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What genes are associated with Glycyrrhetinic acid?

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What common seen animal models are associated with Glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Abe K et al. Determination of 18 beta-glycyrrhetic acid in human plasma by high-performance liquid chromatography. 1994 J. Chromatogr. B, Biomed. Appl. pmid:8012554
Shimamura H et al. Multiple systems for the biliary excretion of organic anions in rats: liquiritigenin conjugates as model compounds. 1994 J. Pharmacol. Exp. Ther. pmid:7965737
Kato M et al. Characterization of the immunoregulatory action of saikosaponin-d. 1994 Cell. Immunol. pmid:7954839
Latif SA et al. Possible endogenous regulators of steroid inactivating enzymes and glucocorticoid-induced Na+ retention. 1994 Steroids pmid:7940612
Mäkelä S et al. Estrogen-specific 17 beta-hydroxysteroid oxidoreductase type 1 (E.C. 1.1.1.62) as a possible target for the action of phytoestrogens. 1995 Proc. Soc. Exp. Biol. Med. pmid:7892295
Chen XG and Han R [Effect of glycyrrhetinic acid on DNA damage and unscheduled DNA synthesis induced by benzo (a) pyrene]. 1994 Yao Xue Xue Bao pmid:7871996
Conti M et al. Renal handling of prednisolone/prednisone: effect of steroid dose and 11 beta-hydroxysteroid dehydrogenase. 1994 Nephrol. Dial. Transplant. pmid:7870352
Albiston AL et al. Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme. 1994 Mol. Cell. Endocrinol. pmid:7859916
Mège RM et al. Is intercellular communication via gap junctions required for myoblast fusion? 1994 Cell Adhes. Commun. pmid:7820536
Takahara T et al. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. 1994 J. Hepatol. pmid:7814808