Glycyrrhetinic acid

Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.

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Introduction

To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycyrrhetinic acid?

Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid

PubChem Associated disorders and diseases

What pathways are associated with Glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Glycyrrhetinic acid?

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What functions are associated with Glycyrrhetinic acid?


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What lipids are associated with Glycyrrhetinic acid?

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What genes are associated with Glycyrrhetinic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Dodds HM et al. Cortisol metabolism and its inhibition by glycyrrhetinic acid in the isolated perfused human placental lobule. 1997 J. Steroid Biochem. Mol. Biol. pmid:9408088
Hundertmark S et al. Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells. 1997 J. Endocrinol. pmid:9390020
Bicíková M et al. Inhibition of rat renal and testicular 11 beta-hydroxysteroid dehydrogenase by some antihypertensive drugs, diuretics, and epitestosterone. 1997 Horm. Metab. Res. pmid:9370118
Cataldo F et al. [Pseudohyperaldosteronism secondary to licorice poisoning associated with hemorrhagic gastritis]. 1997 May-Jun Pediatr Med Chir pmid:9340615
Tordjmann T et al. Coordinated intercellular calcium waves induced by noradrenaline in rat hepatocytes: dual control by gap junction permeability and agonist. 1997 EMBO J. pmid:9311999
Chamberlain JJ and Abolnik IZ Pulmonary edema following a licorice binge. 1997 West. J. Med. pmid:9308417
Best R and Walker BR Additional value of measurement of urinary cortisone and unconjugated cortisol metabolites in assessing the activity of 11 beta-hydroxysteroid dehydrogenase in vivo. 1997 Clin. Endocrinol. (Oxf) pmid:9302399
Fujii M [Pseudoaldosteronism]. 1997 Ryoikibetsu Shokogun Shirizu pmid:9277984
Zhdanov VV et al. [Mechanisms of hemostimulating effect of glyciram]. 1997 Biull Eksp Biol Med pmid:9264711
Heilmann P et al. Determination of 18 beta-glycyrrhetinic acid in human serum using the fully automated ALCA-system. 1997 Eur J Clin Chem Clin Biochem pmid:9263731