MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jayasooriya RG et al. | 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. | 2014 | Toxicol In Vitro | pmid:24613819 |
Chu Y et al. | Preparation and in vitro evaluation of glycyrrhetinic acid-modified curcumin-loaded nanostructured lipid carriers. | 2014 | Molecules | pmid:24566313 |
Ghosh D et al. | Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species. | 2014 | Neurobiol. Aging | pmid:23954169 |
Akopian A et al. | Gap junction-mediated death of retinal neurons is connexin and insult specific: a potential target for neuroprotection. | 2014 | J. Neurosci. | pmid:25100592 |
Li X et al. | Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24380838 |
Yuan R et al. | Self-assembled nanoparticles of glycyrrhetic acid-modified pullulan as a novel carrier of curcumin. | 2014 | Molecules | pmid:25170951 |
Muller B et al. | Glycyrrhetinic acid reverses the lipopolysaccharide-induced hypocontractility to noradrenaline in rat aorta: implications to septic shock. | 2014 | J. Pharmacol. Sci. | pmid:25141925 |
Fujita K et al. | Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact. | 2014 | J. Cell. Biochem. | pmid:25043105 |
Hendricks JM et al. | Differential induction of isolated lymphoid follicles in the gut by 18β-glycyrrhetinic acid. | 2014 | PLoS ONE | pmid:24992099 |
Li JY et al. | Glycyrrhizic acid in the treatment of liver diseases: literature review. | 2014 | Biomed Res Int | pmid:24963489 |