MeSH term | MeSH ID | Detail |
---|---|---|
Ear Diseases | D004427 | 7 associated lipids |
Edema | D004487 | 152 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Ear Diseases | D004427 | 7 associated lipids |
Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jeworutzki E et al. | GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit. | 2012 | Neuron | pmid:22405205 |
Liu Y et al. | Effects of a non-conservative sequence on the properties of β-glucuronidase from Aspergillus terreus Li-20. | 2012 | PLoS ONE | pmid:22347419 |
Gao Z et al. | Induction of apoptosis with mitochondrial membrane depolarization by a glycyrrhetinic acid derivative in human leukemia K562 cells. | 2012 | Cytotechnology | pmid:22274625 |
Zhou X et al. | Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis. | 2012 | Phytother Res | pmid:21656601 |
Kim K et al. | Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters. | 2012 | Mol. Cancer Ther. | pmid:22752225 |
Moon MH et al. | 18β-Glycyrrhetinic acid inhibits adipogenic differentiation and stimulates lipolysis. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22465130 |
Böttger S et al. | Saponins can perturb biologic membranes and reduce the surface tension of aqueous solutions: a correlation? | 2012 | Bioorg. Med. Chem. | pmid:22503361 |
Carbone SE et al. | Loss of responsiveness of circular smooth muscle cells from the guinea pig ileum is associated with changes in gap junction coupling. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22461022 |
Hendricks JM et al. | 18β-glycyrrhetinic acid delivered orally induces isolated lymphoid follicle maturation at the intestinal mucosa and attenuates rotavirus shedding. | 2012 | PLoS ONE | pmid:23152913 |
Zhong H et al. | [Roles of gap junctions in proliferation mediated by Hcy in the spontaneous hypertensive rat vascular smooth muscle cells]. | 2012 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:23156716 |