MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Le AC and Musil LS | Normal differentiation of cultured lens cells after inhibition of gap junction-mediated intercellular communication. | 1998 | Dev. Biol. | pmid:9851844 |
Yamamoto Y et al. | Endothelium-dependent hyperpolarization and intercellular electrical coupling in guinea-pig mesenteric arterioles. | 1999 | J. Physiol. (Lond.) | pmid:9852331 |
Takechi M et al. | Structure-activity relationships of saponins and cardiac glycosides. III. Beta-L-xylopyranosyl-(1-->6)-alpha- and -beta-D-glucopyranosides. | 1998 | Biol. Pharm. Bull. | pmid:9853422 |
Reuss B et al. | Gap junction uncoupling of neonatal rat astroglial cultures does not affect their expression of fibroblast growth factor 2. | 1998 | Neurosci. Lett. | pmid:9876048 |
Harada S et al. | Biochemical characterization of recombinant HIV-1 reverse transcriptase (rRT) as a glycyrrhizin-binding protein and the CK-II-mediated stimulation of rRT activity potently inhibited by glycyrrhetinic acid derivative. | 1998 | Biol. Pharm. Bull. | pmid:9881639 |
Miyake T et al. | [Absorption, excretion, and distribution of beta-glycyrrhetinic acid in mice]. | 1976 | Kaku Igaku | pmid:988351 |
Shaikh ZA et al. | Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. | 1999 | Toxicol. Appl. Pharmacol. | pmid:9931285 |
Akao T | Purification and characterization of glycyrrhetic acid mono-glucuronide beta-D-glucuronidase in Eubacterium sp. GLH. | 1999 | Biol. Pharm. Bull. | pmid:9989667 |