MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hayashi H et al. | Characterization of a glycyrrhizin-deficient strain of Glycyrrhiza uralensis. | 2013 | Biol. Pharm. Bull. | pmid:23995656 |
Wu F et al. | Glycyrrhetinic acid-poly(ethylene glycol)-glycyrrhetinic acid tri-block conjugates based self-assembled micelles for hepatic targeted delivery of poorly water soluble drug. | 2013 | ScientificWorldJournal | pmid:24376388 |
Kim ME et al. | 18β-Glycyrrhetinic acid from licorice root impairs dendritic cells maturation and Th1 immune responses. | 2013 | Immunopharmacol Immunotoxicol | pmid:23438306 |
Figueroa XF et al. | Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. | 2013 | Neuropharmacology | pmid:23499665 |
Yamaguchi H et al. | Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies. | 2013 | Biochem. Pharmacol. | pmid:23791871 |
Ishida T et al. | Effect of 18β-glycyrrhetinic acid and hydroxypropyl γcyclodextrin complex on indomethacin-induced small intestinal injury in mice. | 2013 | Eur. J. Pharmacol. | pmid:23792039 |
Guo XL et al. | Glycyrrhizic acid attenuates CClâ‚„-induced hepatocyte apoptosis in rats via a p53-mediated pathway. | 2013 | World J. Gastroenterol. | pmid:23840116 |
Kato Y et al. | Inhibitors of ATP release inhibit vesicular nucleotide transporter. | 2013 | Biol. Pharm. Bull. | pmid:24189413 |
Lee KW and Ho WS | 18β-glycyrrhetinic acid induces UDP-glucuronosyltransferase in rats. | 2013 | Protein Pept. Lett. | pmid:24261979 |
Cheng M et al. | Synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and its inhibition of liver cancer characteristics in vitro and in vivo. | 2013 | Mar Drugs | pmid:24048270 |