MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cameron BD et al. | The absorption of [G-3H]-acetylglycyrrhetate after oral administration to rats. | 1976 | Arzneimittelforschung | pmid:1036700 |
Lin G et al. | The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats. | 1999 | Toxicon | pmid:10400287 |
Odaka A et al. | [Effect of beta-glycyrrhizinate on eye mucosa absorption of drugs]. | 1999 | Yakugaku Zasshi | pmid:10434802 |
Hu WY et al. | The induction of liver microsomal cytochrome P450 by Glycyrrhiza uralensis and glycyrrhetinic acid in mice. | 1999 | Biomed. Environ. Sci. | pmid:10442216 |
Feinstein MB and Schleimer RP | Regulation of the action of hydrocortisone in airway epithelial cells by 11beta-hydroxysteroid dehydrogenase. | 1999 | Am. J. Respir. Cell Mol. Biol. | pmid:10460758 |
Griffith TM and Taylor HJ | Cyclic AMP mediates EDHF-type relaxations of rabbit jugular vein. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10486252 |
Tanaka Y et al. | Glycyrrhetinic acid-sensitive mechanism does not make a major contribution to non-prostanoid, non-nitric oxide mediated endothelium-dependent relaxation of rat mesenteric artery in response to acetylcholine. | 1999 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:10509734 |
Guillaume CP et al. | Determination of urinary 18 beta-glycyrrhetinic acid by gas chromatography and its clinical application in man. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10510787 |
Bertuzzi F et al. | Mechanisms of coordination of Ca2+ signals in pancreatic islet cells. | 1999 | Diabetes | pmid:10512361 |
Horigome H et al. | Glycyrrhetinic acid-induced apoptosis in thymocytes: impact of 11beta-hydroxysteroid dehydrogenase inhibition. | 1999 | Am. J. Physiol. | pmid:10516121 |