| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Ear Diseases | D004427 | 7 associated lipids |
Total
2
Glycyrrhetinic acid
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
Cross Reference
Introduction
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glycyrrhetinic acid?
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
PubChem Associated disorders and diseases
What pathways are associated with Glycyrrhetinic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glycyrrhetinic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Glycyrrhetinic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Glycyrrhetinic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gong H et al. | A protective mechanism of licorice (Glycyrrhiza uralensis): isoliquiritigenin stimulates detoxification system via Nrf2 activation. | 2015 | J Ethnopharmacol | pmid:25557030 |
| Yang H et al. | The protection of glycyrrhetinic acid (GA) towards acetaminophen (APAP)-induced toxicity partially through fatty acids metabolic pathway. | 2015 | Afr Health Sci | pmid:26957996 |
| Chen Q et al. | Preparation and characterization of glycyrrhetinic acid-modified stearic acid-grafted chitosan micelles. | 2015 | Artif Cells Nanomed Biotechnol | pmid:24093764 |
| Lv QL et al. | In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4. | 2015 | Int J Environ Res Public Health | pmid:26712778 |
| Mezghrani O et al. | Hepatocellular carcinoma dually-targeted nanoparticles for reduction triggered intracellular delivery of doxorubicin. | 2015 | Int J Pharm | pmid:25455765 |
| Chang J et al. | Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways. | 2015 | PLoS ONE | pmid:26011146 |
| Qu Y et al. | Effects of 18α-glycyrrhizin on TGF-β1/Smad signaling pathway in rats with carbon tetrachloride-induced liver fibrosis. | 2015 | Int J Clin Exp Pathol | pmid:25973013 |
| Chen J et al. | A novel glycyrrhetinic acid-modified oxaliplatin liposome for liver-targeting and in vitro/vivo evaluation. | 2015 | Drug Des Devel Ther | pmid:25945038 |
| Schrobback K et al. | The importance of connexin hemichannels during chondroprogenitor cell differentiation in hydrogel versus microtissue culture models. | 2015 | Tissue Eng Part A | pmid:25693425 |
| Gupta P et al. | Antileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activation. | 2015 | Antimicrob. Agents Chemother. | pmid:25691644 |
| Sigurjónsdóttir Hà and Wallerstedt S | [Licorice--so much more than candy]. | 2015 | Lakartidningen | pmid:25689012 |
| Zhu J et al. | Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway. | 2015 | Int. J. Oncol. | pmid:25573651 |
| Mirza MU et al. | Glycyrrhetinic acid and E.resveratroloside act as potential plant derived compounds against dopamine receptor D3 for Parkinson's disease: a pharmacoinformatics study. | 2015 | Drug Des Devel Ther | pmid:25565772 |
| Qi WW et al. | Doxorubicin-loaded glycyrrhetinic acid modified recombinant human serum albumin nanoparticles for targeting liver tumor chemotherapy. | 2015 | Mol. Pharm. | pmid:25584860 |
| Bhatia C et al. | Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. | 2015 | Chem. Biol. Interact. | pmid:25526675 |
| Sakamoto S et al. | Effect of glycyrrhetinic acid on lipid raft model at the air/water interface. | 2015 | Biochim. Biophys. Acta | pmid:25445675 |
| Kølvraa M et al. | Mechanisms contributing to cluster formation in the inferior olivary nucleus in brainstem slices from postnatal mice. | 2014 | J. Physiol. (Lond.) | pmid:24042500 |
| Zhang W et al. | [Inhibitory effect of 18β-glycyrrhetinic acid on KCl- and PE-induced constriction of rat renal interlobar artery in vitro]. | 2014 | Sheng Li Xue Bao | pmid:24777410 |
| Mizoguchi K et al. | Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain. | 2014 | PLoS ONE | pmid:24752617 |
| Huang RY et al. | 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. | 2014 | PLoS ONE | pmid:24695790 |