| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Tongue Neoplasms | D014062 | 15 associated lipids |
| Carcinogenesis | D063646 | 3 associated lipids |
Total
3
ursolic acid
Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ursolic acid?
ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ursolic acid
PubChem Associated disorders and diseases
What pathways are associated with ursolic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ursolic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with ursolic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with ursolic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with ursolic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with ursolic acid?
Mouse Model
Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).
Knock-out
Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Cancer Model
Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with ursolic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Aggarwal BB and Shishodia S | Molecular targets of dietary agents for prevention and therapy of cancer. | 2006 | Biochem. Pharmacol. | pmid:16563357 |
| Zhang GP et al. | [Effect of ursolic acid on caspase-3 and PARP expression of human MCF-7 cells]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:16570804 |
| Thuong PT et al. | Anti-complementary activity of ursane-type triterpenoids from Weigela subsessilis. | 2006 | Biol. Pharm. Bull. | pmid:16595930 |
| Moon HK et al. | Protection of peroxynitrite-induced DNA damage by dietary antioxidants. | 2006 | Arch. Pharm. Res. | pmid:16596994 |
| Ahmed Z et al. | Structure determination of ursene-type triterpenes by NMR techniques. | 2006 | Magn Reson Chem | pmid:16607673 |
| Zhang YY et al. | [Mechanisms of inhibiting proliferation and inducing apoptosis of human gastric cancer cell line SGC7901 by ursolic acid]. | 2006 | Ai Zheng | pmid:16613675 |
| pmid:16619351 | ||||
| Aguirre-Crespo F et al. | Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta. | 2006 | Life Sci. | pmid:16630635 |
| Ikeda Y et al. | Ursolic acid enhances cyclooxygenases and tumor necrosis factor-alpha expression in mouse skin. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16636478 |
| Aparecida Resende F et al. | Antimutagenicity of ursolic acid and oleanolic acid against doxorubicin-induced clastogenesis in Balb/c mice. | 2006 | Life Sci. | pmid:16647723 |
| pmid:16678367 | ||||
| Wang MY et al. | [Studies on the chemical constituents from stem of Chirita longgangensis var. Hongyao]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:16706021 |
| Tan J et al. | [Ursolic acid induces apoptosis in colon cancer HT-29 cells]. | 2006 | Zhonghua Zhong Liu Za Zhi | pmid:16750011 |
| Schleich S et al. | Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity. | 2006 | Planta Med. | pmid:16783690 |
| Cui T et al. | Quantification of the polyphenols and triterpene acids in chinese hawthorn fruit by high-performance liquid chromatography. | 2006 | J. Agric. Food Chem. | pmid:16787000 |
| Zhang W et al. | Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake. | 2006 | Biochim. Biophys. Acta | pmid:16828971 |
| Ma X et al. | [Determination of ursolic acid in Ledum palustre L. by RP-HPLC]. | 2006 | Se Pu | pmid:16830480 |
| Ovesná Z et al. | Protective effects of ursolic acid and oleanolic acid in leukemic cells. | 2006 | Mutat. Res. | pmid:16831451 |
| Lans C et al. | Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada. | 2006 | J Ethnobiol Ethnomed | pmid:16893454 |
| pmid:16920301 |