ursolic acid

Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ursolic acid?

ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ursolic acid

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Carcinogenesis D063646 3 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with ursolic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ursolic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ursolic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ursolic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ursolic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ursolic acid?

Mouse Model

Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).

Knock-out

Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Cancer Model

Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ursolic acid

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Authors Title Published Journal PubMed Link
pmid:26867795
pmid:26854375
pmid:26847129
pmid:26797293
pmid:26794949
Lin H et al. Targeting Th17 Cells with Small Molecules and Small Interference RNA. 2015 Mediators Inflamm. pmid:26792955
Blanchaert B et al. Bioanalytical LC/MS study of potential bacterial transglycosylation inhibitors. 2016 J Pharm Biomed Anal pmid:26782294
pmid:26777089
pmid:26775565
Luna-Vázquez FJ et al. Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits. 2016 Molecules pmid:26771591
pmid:26750249
pmid:26719288
pmid:26711605
pmid:26686287
Yamamoto ES et al. The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis. 2015 PLoS ONE pmid:26674781
pmid:26657265
pmid:26634867
pmid:26619955
Woźniak Ł et al. Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities. 2015 Molecules pmid:26610440
Zhang X et al. p21 induction plays a dual role in anti-cancer activity of ursolic acid. 2016 Exp. Biol. Med. (Maywood) pmid:26582056